The CBD utilized in our tinctures is extracted from industrial hemp cultivated in the United States. To further ensure quality and purity, our industrial hemp goes through a supercritical CO2 extraction process to obtain the best possible CBD solution. This solution is then formulated by our board-certified pharmacists into finished products and sent out for third-party testing. Our CBD oil is made with high-quality CBD extracted from organic hemp that is abundant in naturally produced terpenes, oils, vitamins, omega fatty acids, and other components.
No, you *are no expert*–so you have no business making a diagnosis sight unseen. “Leaky gut” and “gluten sensitivity” (as opposed to celiac disease, which is legit) are among the trendy diagnoses du jour. You don’t know these folks’ diets, specific symptoms or official diagnoses. Don’t give me any blather about “Big Pharma,” “suppressing natural cures, “or the “medical industry conspiracy,” either. (“Suppression?” I get my CBD oil from an actual MD, with the approval of my oncologist).
While researchers are calling for more robust studies on the role of CBD on mood disorders, there is promising research that points to CBD’s role as an anxiolytic – which means it has anti-anxiety effects. Another study showed CBD to have antidepressant effects comparable to those of the prescription antidepressant Imipramine. We noted above that CBD increases levels of glutamate and serotonin – and it’s these same neurotransmitters that play a crucial role in mood regulation.
In addition to acting on the brain, CBD influences many body processes. That’s due to the endocannabinoid system (ECS), which was discovered in the 1990s, after scientists started investigating why pot produces a high. Although much less well-known than the cardiovascular, reproductive, and respiratory systems, the ECS is critical. “The ECS helps us eat, sleep, relax, forget what we don’t need to remember, and protect our bodies from harm,” Marcu says. There are more ECS receptors in the brain than there are for opioids or serotonin, plus others in the intestines, liver, pancreas, ovaries, bone cells, and elsewhere.
Basically, cannabis is an umbrella term that includes both hemp and marijuana plants. Cannabis sativa is actually the scientific name of the cannabis plant (Cannabis = genus; sativa = species), and hemp and marijuana are just two different “varieties” of it (i.e. you could refer to both marijuana and hemp plants as “cannabis” plants, but you would not, for instance, refer to a “marijuana” plant as a “hemp” plant). Hopefully that’s not too confusing.
CBD isolate is derived from the hemp plant via various processes. These processes make extraction and isolation of CBD possible. Typically, the process of producing CBD isolate starts with growing hemp organically. This is not the cannabis strain that gets users high. The isolate is produced from a commercial-grade, industrial hemp. Basically, this is the cannabis that is grown to produce maximum biomass. It’s important to note that hemp is different from marijuana that is found in the streets and used by people that want to get high. However, both hemp and marijuana are technically similar plants. The only difference is that hemp has THC in low amounts and CBD in high amounts.
Although CBD oils aren’t regulated by the FDA, purchasing products stateside from one of the nine states where recreational and medical cannabis use is legal will likely result in a higher-quality product than buying one made with hemp-derived CBD oil imported from abroad, says Martin Lee, director of Project CBD, a nonprofit that promotes medical research into CBD.
Up until recently, it was the psychoactive component of cannabis, tetrahydrocannabinol (THC), which received most of the attention for its medicinal benefits, as well as its ability to produce psycho- tropic effects. Now, with medical marijuana gaining ground across the country, researchers are discovering the amazing properties of additional cannabinoids. But what makes CBD so special?
Hi Chris, the whole “product labeling” thing from brand to brand is definitely super confusing. Because the industry is so unregulated, companies can label their products “hemp oil,” “CBD oil,” “hemp extract oil,” etc, and there’s really no way to distinguish between them or tell what’s actually in them — unless they have a lab report. Basically, if you don’t see the word “CBD” anywhere on the label or on the product description, the oil is probably made from hemp seeds (in which case it has no CBD). The only sure way to know you’re getting an oil with CBD in it is to find something with a certified lab report showing the exact amount of CBD (and even still, some companies have been known to fudge their way around this). I know this isn’t the most clear-cut answer, but again, given how unregulated the industry is, there’s really no “perfect” answer. Hope this helps a little bit 🙂

Cannabidiol has been found to act as an antagonist of GPR55, a G protein-coupled receptor and putative cannabinoid receptor that is expressed in the caudate nucleus and putamen in the brain.[35] It has also been found to act as an inverse agonist of GPR3, GPR6, and GPR12.[12] Although currently classified as orphan receptors, these receptors are most closely related phylogenetically to the cannabinoid receptors.[12] In addition to orphan receptors, CBD has been shown to act as a serotonin 5-HT1A receptor partial agonist,[36] and this action may be involved in its antidepressant,[37][38] anxiolytic,[38][39] and neuroprotective effects.[40][41] It is an allosteric modulator of the μ- and δ-opioid receptors as well.[42] The pharmacological effects of CBD have additionally been attributed to PPARγ agonism and intracellular calcium release.[8]

Dry mouth: As is the case with many other hemp- and marijuana-based products, CBD oil often leads to a condition known as dry mouth (or cottonmouth). This is likely due to cannabinoids altering receptors in the lower jaw that trigger salivation. In most cases, mild discomfort and stronger-than-average thirst are the only issues associated with dry mouth.

Selective breeding of cannabis plants has expanded and diversified as commercial and therapeutic markets develop. Some growers in the U.S. succeeded in lowering the proportion of CBD-to-THC to accommodate customers who preferred varietals that were more mind-altering due to the higher THC and lower CBD content.[58] Hemp is classified as any part of the cannabis plant containing no more than 0.3% THC in dry weight form (not liquid or extracted form).[59]
These statements have not been evaluated by the fda and are not intended to diagnose, treat, or cure any disease. Always check with your physician before starting a new dietary supplement program. Leaving our website disclaimer: if we have a research link to a website where we sell products or have product information, the exit disclaimer indicates that when you click ok you will leave the dixiebotanicals.com website and visit an external link. Links to any informational websites are provided solely as a service to our users. External links provide additional information that may be useful or interesting and has no affiliation to the promotion, sale and distribution of dixie botanicals products. The link does not constitute an endorsement of these organizations by dixie botanicals and none should be inferred. Please view our full terms of use agreement for more information and the terms and conditions governing your use of this site.
Jump up ^ Devinsky, Orrin; Cilio, Maria Roberta; Cross, Helen; Fernandez-Ruiz, Javier; French, Jacqueline; Hill, Charlotte; Katz, Russell; Di Marzo, Vincenzo; Jutras-Aswad, Didier; Notcutt, William George; Martinez-Orgado, Jose; Robson, Philip J.; Rohrback, Brian G.; Thiele, Elizabeth; Whalley, Benjamin; Friedman, Daniel (22 May 2014). "Cannabidiol: Pharmacology and potential therapeutic role in epilepsy and other neuropsychiatric disorders". Epilepsia. 55 (6): 791–802. doi:10.1111/epi.12631. PMC 4707667. PMID 24854329.
Watch Out For: Hemp grown in China. Even in countries with agricultural regulations, the list of approved pesticides is far from safe. Thus you are really relying on the specific company’s ethical standards when it comes to hemp cultivation. The reason this is such a big deal with hemp when compared to other plants, is that hemp is a dynamic accumulator plant. Dynamic accumulator is a term used to describe plants that gather minerals – both good and bad – from the surrounding soil and store them in its tissues. So if you’re growing a hemp plant with petroleum-based pesticides in soil that contains heavy metals…you’re inevitably going to have a hemp plant containing both toxic pesticides and heavy metals. This is why many people have poor experiences when first trying CBD – you buy your vegetables organically, why not your hemp? The presence of these toxins is not regulated by any agency and they will end up in your CBD oil if you don’t purchase from the correct company. We like Ambary Gardens because they ensure that all of their CBD products are produced from organically and sustainably grown hemp without the use of pesticides.

Canabidol™ Oral Capsules deliver 100% Cannabis Sativa L. from specifically bred industrial hemp plants containing high potency Cannabidiol. Each CBD capsule contains all the Cannabinoids, terpenoids, essential oils and all the other compounds of the cannabis plant. A packet of 30 capsules contains 15,000mg of Cannabis Sativa L. and 300mg of CBD (Cannabidiol) Each capsule contains 500mg of Cannabis Sativa L. and 10mg of the active ingredient CBD
Hemp is a bioaccumulator, meaning it is capable of absorbing both the good and the bad from the air, water, and soil in which it’s grown. This makes it all the more important to know that your CBD oil comes from organically grown hemp that can be tracked to its US-grown source. The last thing buyers want is for their CBD oil to have accumulated toxic substances such as pesticides, herbicides, or heavy metals. For decades, farmers have used pesticides to protect crops against insects, disease, and fungi – and have used herbicides to control weeds – but we’ve known for quite some time that chemicals used to harm other species can also be harmful to our own species. That’s one big reason behind the global push to go organic. People are starting to prioritize organic crops, whether you’re talking about fruits, vegetables, grains, legumes, nuts, livestock feed – even textiles like cotton, wool, and flax.
Various strains of "medical marijuana" are found to have a significant variation in the ratios of CBD-to-THC, and are known to contain other non-psychotropic cannabinoids.[61] Any psychoactive marijuana, regardless of its CBD content, is derived from the flower (or bud) of the genus Cannabis. Non-psychoactive hemp (also commonly-termed industrial hemp), regardless of its CBD content, is any part of the cannabis plant, whether growing or not, containing a ∆-9 tetrahydrocannabinol concentration of no more than three-tenths of one percent (0.3%) on a dry weight basis.[62] Certain standards are required for legal growing, cultivating and producing the hemp plant. The Colorado Industrial Hemp Program registers growers of industrial hemp and samples crops to verify that the THC concentration does not exceed 0.3% on a dry weight basis.[62]

Among the most versatile CBD product available, RSHO™ isolate can be consumed using a variety of methods. Consume it as-is by placing it under your tongue, or add it to various foods and beverages. Vape or dab crystallized RSHO™ CBD isolate by blending it with your favorite botanical vaping liquids. CBD isolate powder is oil-soluble, so you can mix it with coconut, hemp or MCT oil to create your own CBD oils or tinctures, which can then be absorbed sublingually under the tongue before being swallowed.
Before I even checked the ingredients list and saw that cocoa seed butter was involved, my first impression was that this body butter smelled like chocolate, so much so that my stomach rumbled with hunger because it was 4pm and I hadn’t eaten lunch yet. Don’t the “whipped” descriptor fool you—unlike most body butters you’ve used, this formula is solid to the touch, a balm rather than a cream. But that might be exactly what you want if you’re looking for a CBD-infused treatment anyway—something that feels extra-nourishing and almost medicinal. Luckily, it smells incredible in a subtle, natural way, not like other body butters with artificial tropical fruit scents.
The topical menthol ointment is our most common product for direct application to sore joints, muscle tissue, and damaged skin areas. Standard CBD oil drops can take up to an hour (or longer) to take effect (since they have to enter into the bloodstream), but with topical creams, effects are typically felt within minutes as the active cannabidiol simply has to diffuse across the dermal layers and to the site of inflammation.
I’ve been hoarding Girl Scouts Thin Mints lately (they’re especially good if you freeze them)—the chocolate is fine, but the peppermint oil is what makes them addicting enough to go through a whole sleeve without getting sick of them. I’m also trying to cut down on sugar, though, and while it would be a huge stretch to say that this peppermint oil-infused clear lip balm is a direct replacement for Girl Scout cookies, it really does have a very satisfying full-mouth taste of peppermint. The CBD oil, which soothes and facilitates healing at the same time, makes this formula an ideal balm for outdoor enthusiasts and or just those who are prone to painfully chapped lips. For those of us with long-hair-don’t-care, it’s not sticky—as a matter of fact, the formula is on the stiff side and won’t cause your hair to stick to your face, a welcome departure from many balms.

Our CBD Hemp Oils are extracted from our own proprietary strain of hemp grown specifically for pets, PR-33.  This strain is grown at the largest certified USDA organic hemp farm in the United States. Our joint-partnership with our farmers allows us to have complete control over our hemp plants, from seed to sale, from plant to pet we know exactly what’s going into the products you’re giving your pets.
CBD is showing real promise as a compound that can contribute to protecting the brain, thanks to its anti-oxidant and anti-inflammatory abilities. Scientists are investigating its role in neurogenesis and its ability to help the brain heal from injury, and as a treatment for neurodegenerative disease. Research suggests that CBD may help to reduce brain damage from stroke or other neurological injury. And CBD is increasingly looked to as a possible therapy for several neurodegenerative diseases, including Parkinson’s, Alzheimer’s, and multiple sclerosis.
Joseph Rosenblatt is a New York entrepreneur and COO of Enliven Essentials, a New York CBD-infused-product company. He helped found Enliven Essentials with his family when he discovered the astonishing benefits CBD oil could provide for close family members suffering from pain and anxiety. Rosenblatt also writes, travels, and educates people about CBD oil and the benefits it carries. He can be reached at joseph@enlivenessentials.com or through enlivenessentials.com.
If you just don’t have the time or inclination to take supplements every day, but you still want to experience the potential benefits of CBD, this Hemp Oil CBD Patch from Pure Ratios could be just what you’re looking for. With little fuss or need for specialist know-how or equipment, simply apply a patch to the target area and enjoy a slow-release 40-mg serving of CBD that will last for up to 96 hours.
 These products are not psychoactive, they will not get a person 'high', and they will not cause a person to fail a drug test. Ice Moon cycle batch January 2018 -- 1085 mg of CBD per 8 ounce jar The CBD salve contains the following ingredients: 77.2% solid coconut oil infused with hemp 14.5% beeswax 3.8% liquid coconut oil infused with hemp 1.6% Vitamin E oil 1.5% calendula oil 1.4% lavender oil All products are tested for potency. 
Every BioCBD Plus™ product is more than just water soluble CBD. All of our products feature a proprietary Ayurvedic blend of water soluble cannabinoids, terpenes and different Ayurvedic herbs. We understand the desire to know the exact amounts of ingredients in each of our Ayurvedic blends, and we wish we could share that information with you without jeopardizing our trade secrets. What we can share with you is this Ayurvedic blend is Hemp Oil (CBD), Curcumin, Eucalyptus, Ginger, White Willow Bark & Burseraceae).
Sagely Naturals tests its products three times: the raw cannabidiol is evaluated by extractors, then by another third party lab. Finally, when the company receives the final product, Sagely randomly selects bottles to test for the third and final time. These tests ensure that the product is devoid of GMOs, solvents, chemicals, heavy metals, pesticides, herbicides, and THC.
With the rapid growth of the CBD industry and constant advances in its technology, there are a lot of terms floating around that are unfamiliar, if not confusing, to many people. “Nano-Amplified CBD” is one of them. While the science and biological make-up of CBD is the subject of much research and scholarly articles, it can all be broken down into simple terms.
Canabidol™ CBD cannabis oil (CBD Oli) is derived from EU approved, UK & US legal, industrial hemp (Cannabis Sativa L.) The active ingredient is Cannabidiol as our products are THC free, meaning that they are non psychoactive so will not get you high. CBD Oil (Cannabidiol) is not scheduled and is found in all hemp products which makes it legal in both the UK and US. Manufactured in England to the highest standards Canabidol™ is now sent out from our United Kingdom distribution centre.  You can also purchase our range of CBD oil products direct from one of our many stores across the UK.
I recommend changing your diet. There isn’t anything topical that will help you. It must come from within. For week, follow a whole food plat based diet, oil free. not even olive oil or coconut oil. Look up, Dr Mc Dougall’s recipes. He has thousands of recipes. Also Cooking with Plants also has awesome mouth watering easy to prepare recipes. Your body will heal and your life will change.
The CBD utilized in our tinctures is extracted from industrial hemp cultivated in the United States. To further ensure quality and purity, our industrial hemp goes through a supercritical CO2 extraction process to obtain the best possible CBD solution. This solution is then formulated by our board-certified pharmacists into finished products and sent out for third-party testing. Our CBD oil is made with high-quality CBD extracted from organic hemp that is abundant in naturally produced terpenes, oils, vitamins, omega fatty acids, and other components.
Most human studies of CBD have been done on people who have seizures, and the FDA recently approved the first CBD-based drug, Epidiolex, for rare forms of epilepsy. Clinical trials for other conditions are promising, but tiny. In one Brazilian study published in 2011 of people with generalized social anxiety disorder, for example, taking a 600-mg dose of CBD (higher than a typical dose from a tincture) lessened discomfort more than a placebo, but only a dozen people were given the pill.
Buying CBD OIL has never been easier.  Since CBD Oil from the Hemp plant does not contain unlawful measures of THC, it is legitimate in every one of the 50 states. This is imperative to individuals everywhere throughout the US who need CBD however can’t get it locally. What’s more, legitimate CBD is accessible for home conveyance in every one of the 50 states meaning numerous individuals don’t need to move to a state with sanctioned Medical Marijuana. Additionally, in states where medicinal weed is lawful, buyers utilizing this hemp plant type of CBD don’t need to obtain a medical marijuana card.

According to a recent publication from 2017, research has determined that CBD has a good safety profile, especially when compared to pharmaceuticals. The researchers concluded that “the most commonly reported side effects were tiredness, diarrhea, and changes of appetite/weight. In comparison with other drugs… CBD has a better side effect profile.” (2)
Disclaimer: This product is not for use by or sale to persons under the age of 18. The statements made regarding these products have not been evaluated by the Food and Drug Administration. The efficacy of these products has not been confirmed by FDA-approved research. These products are not intended to diagnose, treat, cure or prevent any disease. All information presented here is not meant as a substitute for or alternative to information from health care practitioners. Please consult your health care professional about potential interactions or other possible complications before using any product. The Federal Food, Drug and Cosmetic Act requires this notice.
I have this issue with neuropathy in my feet and it drives me crazy. Cant’ sleep etc… I tried some high dose CBD cream (myaderm) works really well for me. It didn’t cure anything but this is the only cream I could find that where the CBD actually stopped the pain. I think it’s because of how it’s delivered (transdermally). That seems to get down to business faster then the other ones I tried. I put some on before I go to bed and it allows me to sleep painlessly and I don’t need to take any additional pain killers… my not a doctor but it’s worth a try.

The following medications and other supplements may interact with CBD. Effects may include increasing or decreasing sleepiness and drowsiness, interfering with the effectiveness of the medications or supplements, and interfering with the condition that is being treated by the medication or supplement. These are lists of commonly used medications and supplements that have scientifically identified interactions with CBD. People who take these or any other medications and supplements should consult with a physician before beginning to use CBD.


Ian Jones is a journalist based in Manchester, England. He specialises in technology and food, with a heavy focus on vaping, CBD and medicinal drugs. He began writing professionally over 15 years ago and is a regular contributor to New Scientist, Vice and the Daily Mirror. He is also the resident CBD expert at the respected vaping website Spinfuel. He began looking at CBD in detail after discovering that it cured his mother's arthritis, and has since become a leading figure in the UK when it comes to educating people about the CBD extraction process and exploring its curative properties.
Locsta....I share your pain of degenerative and bulging disk disease, along with fibromyalgia, chronic fatigue and arthritis. Absolutely no energy and chronic pain all day, every day. I'm curious as to what type and brand of the CBD oil you are taking and for how long have you been using it? I've been researching CBD oil for months and am quite confused!
Scientists have made a lot of progress in understanding how CBD produces its calming, pain-reducing, anti-inflammatory effects in the body—and there’s still more to learn. We know that CBD interacts with many different receptors, proteins, and other chemicals in the brain. These interactions create changes in the activity of neurotransmitters, hormones, and other cells throughout the brain and body. Through these interactions, CBD appears to be able to affect many of the body’s functions, from sleep-wake cycles and emotional regulation to inflammation, pain perception, and seizures.

Topicals are applied right to trouble areas so that the CBD oil can work directly where it’s needed most. Ingesting CBD products orally causes CBD and other compounds to enter the blood stream, which elicits full-body effects and takes up to 2 hours or more before those effects are experienced. With CBD topicals, the healing compound and other hemp-derived nutrients are almost immediately absorbed directly through your skin, allowing them to be target the affected area for quicker and more focused effects.  


"It’s been shown that THC and CBD, when combating the myriad of symptoms and disease states, have a synergistic relationship," explains Steve Looi, Director of Origination at White Sheep Corp., a Toronto-based cannabis commercial operator and strategic investor with holdings in Canada and the US. "The compounds are more effective in each other’s presence than they would be if taken alone."
Our BioCBD Plus™ products are made of water soluble CBD. In fact we are the original providers of water soluble CBD in the market place. This means that our products are multiple times more effective than CBD Oil due to its higher absorption rate. Add on top of that our nanotechnology and we provide the highest absorption rate in the industry, upwards of 90+%.

Thousands of people have learned about the healing benefits of CBD, resulting in unprecedented interest in this supplement. People are using CBD oil to ease their chronic pain, and relieve symptoms of conditions ranging from arthritis to depression. Unlike its close cousin, psychoactive cannabis (‘marijuana’), CBD oil won’t make you feel high — but many users report significant relief of their symptoms. Even the World Health Organization declared CBD oil safe and worthy of deeper research.
When CBD is referred to as full spectrum or whole plant CBD, it means that the CBD contains all other cannabinoids found in the marijuana plant including CBN (Cannabinol), CBG (Cannabigerol), and THCV (Tetrahydrocannabivarin), to name a few. And yes, along with these cannabinoids, Full Spectrum CBD also contains trace amounts of THC (Tetrahydrocannabinol), but in very low concentrations (up to .3%), resulting in very minimal psychoactive stimulation.
THC and CBD work together.  CBD organically blocks the potency of THC, which makes the high experienced by the consumer manageable and pleasant.  THC works with CBD to amplify its medicinal qualities.  Additionally, THC has medicinal qualities of its own that are completely forgone by CBD isolate. Cannabis has more to offer than just cannabinoids; terpenes, the chemical compounds that create the plant’s scent, are also present in cannabis.
NuLeaf Naturals CBD oil tinctures are all full spectrum; it is 100% organic and never made with herbicides, pesticides, or chemical fertilizers. The brand offers a full spectrum pet CBD oil tincture, as well. NuLeaf Naturals offers free shipping to all 50 states; the brand’s products are also sold in more than 200 retail locations across the country.

My mother has dementia/Alzheimers along with a broken knee that they will not repair do to her mental status. She is currently in a nursing home. I firmly believe her mental situation began with the over use of hydrocodone for over 30 years and was acerbated by the trauma of breaking and disconnecting her knee cap. Since weaning her off of her meds (still in progress) we have regained much of her consciousness. I want to try CBD to help in her recovery or to help slow down the disease. I cannot find a dosage recommendation plus the nursing home/doctor does not recommend it. I would need to give it to her when I am there visiting (about 3 - 4 times per week). Is there a recommended dosage for dementia/Alzheimers?
Watch Out For: Companies who won’t disclose their extraction method or utilize hydrocarbons like butane and propane. These substances are toxic in high amounts and even with proper purging, most hydrocarbon extracts contain residual solvent. Other extraction methods do not result in a full spectrum extract – meaning they were not able to extract all of the beneficial compounds from the hemp plant (i.e. you don’t get the full range of benefits).
Cannabis has been used medicinally for centuries, as a sleep aid, a pain and nausea reducer, to relieve anxiety and other mood problems. In the mid-1960s, scientists identified the first cannabinoid. Since then, scientists have gone on to identify more than 80 individual cannabinoids and continue to investigate them for their potential symptom-relieving and disease-fighting abilities.

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Hi Marilyn, I would recommend a topical lotion or salve to start for instant relief.. Maybe 250 to 300 mg tincture to see how you feel. For me, the salve took the pain in my hands away in under a minute. I didn't notice how much the tincture worked until I forgot to take on vacation. Pain that was pretty much gone but came back, I was tired, grumpy and felt horrible. It works, just need to find right product and dosage for you.
Previously, I had reviewed hemp-based beauty topicals and THC beauty products pioneering the way for cannabis in the skincare industry. This time, I tested the diverse range of CBD oil-based beauty products, which are both potent and legally available for shipping to most states. This is the new frontier in skincare—and these companies are paving the way. Go support them before Sephora hears about this.
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