Upon receipt of our orders, we judged each isolate according to its smell, taste, look, consistency and packaging. While we considered the effects of each CBD isolate, they are all 99%+ CBD and there is little to no difference in the effect of each. All CBD isolate should have the same mellow, non-psychoactive, relaxing and pain-relieving effects. Choosing between these brands comes down mostly to personal preference.

Despite the inability of CBD oil companies to cite health claims linked to their products, people buy CBD oil for pain and inflammation, anxiety, and sleep problems, and some also give it to their pets for the same reasons. In a survey conducted of its customers, CW Hemp, a family-owned provider of lab-tested CBD products, learned the number-one reason people buy their products is for anxiety, and according to a study conducted by Brightfield Group and HelloMD, 70 percent of consumers who use CBD do so because they suffer from anxiety.

NuLeaf Naturals CBD oil tinctures are all full spectrum; it is 100% organic and never made with herbicides, pesticides, or chemical fertilizers. The brand offers a full spectrum pet CBD oil tincture, as well. NuLeaf Naturals offers free shipping to all 50 states; the brand’s products are also sold in more than 200 retail locations across the country.


In order to get CBD out of hemp, it must be extracted. CBD isolate is produced by using a bit of a more detailed extraction process of its own. CBD isolate extraction starts out like other extraction processes used to make CBD. Once the initial extraction takes place, concentrated CBD is still full of all the plant material contained in the hemp plant itself.
Disclaimer: This product is not for use by or sale to persons under the age of 18. The statements made regarding these products have not been evaluated by the Food and Drug Administration. The efficacy of these products has not been confirmed by FDA-approved research. These products are not intended to diagnose, treat, cure or prevent any disease. All information presented here is not meant as a substitute for or alternative to information from health care practitioners. Please consult your health care professional about potential interactions or other possible complications before using any product. The Federal Food, Drug and Cosmetic Act requires this notice.
There is a significant amount of scientific research on CBD and the ECS system as well as journal entries from pilot studies done by doctors from around the world over the past four decades. However, as this is still a novel area of medicine, do your own research on CBD. There are many online sources of information, but note the internet has a mix of both valid and misleading data. Vet your sources to ensure that they are reputable.
CBD concentrates typically contain the strongest dosage of CBD compared to any other CBD products. It can contain up to 10 times the average CBD products. Concentrates are also convenient in that it only takes a few seconds to consume. Overall, CBD concentrates seem to be most popular among customers who are extremely busy, yet seek high potency CBD.
^ Jump up to: a b c d Campos AC, Moreira FA, Gomes FV, Del Bel EA, Guimarães FS (December 2012). "Multiple mechanisms involved in the large-spectrum therapeutic potential of cannabidiol in psychiatric disorders". Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences (Review). 367 (1607): 3364–78. doi:10.1098/rstb.2011.0389. PMC 3481531. PMID 23108553.
A CNN program that featured Charlotte's Web cannabis in 2013 brought increased attention to the use of CBD in the treatment of seizure disorders.[68][69] Since then, 16 states have passed laws to allow the use of CBD products with a doctor's recommendation (instead of a prescription) for treatment of certain medical conditions.[70] This is in addition to the 30 states that have passed comprehensive medical cannabis laws, which allow for the use of cannabis products with no restrictions on THC content.[70] Of these 30 states, eight have legalized the use and sale of cannabis products without requirement for a doctor's recommendation.[70]

It used to be that recreational cannabis users kept their habit on the DL, but now it seems that everyone is tuned into the magic of CBD, from your elderly neighbor using it for glaucoma to the woman in your book group using it for chronic pain relief to the folks at the dog park helping Rusty tone down his anxiety. But what is this magic substance, and more importantly, what can it do for you?


I was diagnosed with fibromyalgia when I was 15. In the past 21 years I’ve tried narcotics, cortizone shots, lidocaine patches, lyrica, cymbalta, acupuncture, and massage. I put this ointment on my shoulders and neck which have been killing me. Instant relief! It’s been over 5 hours and I took a shower and I still don’t feel pain in my shoulders, which is always there. This is a miracle drug. Thank you!!!!
4 oz of CBD salve The Sisters of the Valley make all their products in a spiritual environment, with prayers for the people sown into every bottle and jar. This is a topical or ‘rub-on’ salve with multiple uses. The Sisters’ products are made with high CBD strains of the cannabis plant, strains developed to have virtually no THC. These products are not psychoactive, they will not get a person ‘high’, and they will not cause a person to fail a drug test. The plant material we use to make the products is considered 'hemp' because of the non-psychotropic nature of the plant. USPS delivery to all 50 states and to all international locations. The salve is a topical rub that is used externally. All the Sisters products are made according to moon cycles in a prayerful and spiritual environment. The CBD salve contains the following ingredients: 77.2% solid coconut oil infused with hemp 14.5% beeswax 3.8% liquid coconut oil hemp concentrate 1.6% Vitamin E oil 1.5% calendula oil 1.4% lavender oil Current Batch Quiet Moon, February 2018 >450 mg of CBD per 4 ounce jar All batches are tested for potency. Lab tests available upon request. Hand Made by the Sisters of the Valley in Cooperation with Earth and Sun Keep stored in a cool, dry place (not refrigerate) https://client.sclabs.com/sample/310027/    
Cannabidiol (CBD) has NOT been proven to potentially relieve, relieve, nor cure any severe condition or medical condition listed on this site.  The medical studies, controlled tests, and health information offered on Cannabidiol Life of CBDOilsAndEdibles.com (or any variation of the URL) is an expressed summarization of our personal conducted research done by our team of professionals. The information provided on this site is designed to support, NEVER replace, the relationship that exists between a patient/site visitor and the patient's/site visitor's physician. Our products are not for use by or sale to persons under the age of 18. Our products should be used only as directed on the label. It should not be used if you are pregnant or nursing. Consult with a physician before use if you have a serious medical condition or use prescription medications. A Doctor's advice should be sought before using this and any supplemental dietary product. All trademarks and copyrights are the property of their respective owners and are not affiliated with nor do they endorse this product.  These statements have not been evaluated by the FDA and products listed are not intended to diagnose, potentially relieve, cure or prevent any severe condition. Individual weight loss results will vary. By using this site, you agree to follow the Privacy Policy and all Terms & Conditions printed on this site. Void Where Prohibited by Law.
Upon receipt of our orders, we judged each isolate according to its smell, taste, look, consistency and packaging. While we considered the effects of each CBD isolate, they are all 99%+ CBD and there is little to no difference in the effect of each. All CBD isolate should have the same mellow, non-psychoactive, relaxing and pain-relieving effects. Choosing between these brands comes down mostly to personal preference.

Hi Chris, the whole “product labeling” thing from brand to brand is definitely super confusing. Because the industry is so unregulated, companies can label their products “hemp oil,” “CBD oil,” “hemp extract oil,” etc, and there’s really no way to distinguish between them or tell what’s actually in them — unless they have a lab report. Basically, if you don’t see the word “CBD” anywhere on the label or on the product description, the oil is probably made from hemp seeds (in which case it has no CBD). The only sure way to know you’re getting an oil with CBD in it is to find something with a certified lab report showing the exact amount of CBD (and even still, some companies have been known to fudge their way around this). I know this isn’t the most clear-cut answer, but again, given how unregulated the industry is, there’s really no “perfect” answer. Hope this helps a little bit 🙂
Grown and extracted from the USA, our quality CBD is fully compliant under the Kentucky Department of Agricultural Industrial Hemp Pilot Program. Our CBD products are legal and shipped to all 50 states and internationally. All of our CBD products contain 0% THC, guaranteed. We utilize a whole plant CO2 extraction that allows us to draw the CBD from the plant material and filter out unnatural substances, maximizing pure CBD concentration. Each and every product that leaves the facility is third-party tested to ensure consistency and quality.
Topicals are applied right to trouble areas so that the CBD oil can work directly where it’s needed most. Ingesting CBD products orally causes CBD and other compounds to enter the blood stream, which elicits full-body effects and takes up to 2 hours or more before those effects are experienced. With CBD topicals, the healing compound and other hemp-derived nutrients are almost immediately absorbed directly through your skin, allowing them to be target the affected area for quicker and more focused effects.
There is a lot of confusion out there. Both industrial hemp & marijuana are separate strains of the cannabis plant (hemp is c. sativa and marijuana can be either other strains of c. sativa or c. indica–marijuana has much, much more THC than hemp, which has little-to-none). The site is reviewing only CBD oils made from industrial hemp (more expensive from flower, cheaper & weaker from seeds & stalks) because those are the only kinds of CBD oil one can buy in all 50 states anywhere (not just licensed dispensaries), whether the state allows recreational weed, medical marijuana with an official cannabis ID card, or no marijuana whatsoever for any purpose.
CBD infused skin products made by Cannabis Beauty Defined are also quite popular. This is a line of skin care products with anti-aging properties. They include moisturizers, toners, exfoliators, and serums along the CBD oil. There are also a mixture of herbal extracts included to make sure the skin is well pampered. The result is a smoother, more youthful appearance to the treated area.
Any and all statements made in the ISODIOL blog in regard to Cannabinoid products are not expressed as medical claims. Our intention is to educate, not to suggest results nor to encourage action on the part of the reader. ISODIOL is not responsible for, and expressly disclaims all liability for, damages of any kind arise out of use, refrence to, or reliance on any information contained within the site. The information contained within the site is periodically updated, there is no gurantee to the accuracy of the information. Nothing on this site is intended to operate as legal advice, please seek your own legal advice.
To further ensure the reliability of our CBD isolate, we hold it to the same strict Triple Lab Tested™ standard that all HempMeds® products must go through. This lab testing process uses ISO/IEC 17025:2005 accredited testing labs to carefully examine our hemp oil. These labs test our hemp oil for an accurate concentration of cannabinoids and the presence of mold, mildew, fungus, toxins, heavy metals, and residual solvents to protect the end user from any contamination.
NuLeaf Naturals is headquartered in Colorado, but we ship anywhere in the US. All of our organic CBD oil products will be sent to you via USPS, FedEx, or UPS and should arrive in just 2-3 business days. We offer special pricing options for bulk orders. If you sell health and wellness products and would be interested in promoting medical cannabis oil, consider becoming a wholesale CBD oil partner with us.
My husband has RSD and we are considering CBD oil -= I would ask at Hempmed because the spray won't have enough in it. Our dgt';s friend has ovarian cancer and it is shrinking her tumors but the spray would never have been enough. I would get CBD oil and check with Hempmeds to see what they suggest. It isn't cheap but it does work. LOW dose Naltrexone about 4.5 mg is very helpful for RSD and is usually used for getting people off of drugs but is working on turning off the glial cells that surround the nerve that is causing the nerve to scream in pain. We are also using PeaPure that is out of the Netherlands and we are seeing a response, even though small. His other leg touched the painful leg without causing more severe pain. That is progress. We also are using Poison Ivy Cream through Meadowlake Farms that has helped the burning surface pain. Change your diet and get rid of Gluten and Sugar, anything that causes inflammation. This is to allow your own body to work. Absolutely do not use any pain killers as it will turn up your pain. all the Hydrocodone, etc causes neural inflammation and so it will keep cascading higher your pain. Hope this is helpful. Mary
This article may contain certain forward-looking statements and information, as defined within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934, and is subject to the Safe Harbor created by those sections. This material contains statements about expected future events and/or financial results that are forward-looking in nature and subject to risks and uncertainties. Such forward-looking statements by definition involve risks, uncertainties.
Side effects of CBD include sleepiness, decreased appetite, diarrhea, fatigue, malaise, weakness, sleeping problems, and others.[3] It does not have intoxicating effects like those caused by THC, and may have an opposing effect on disordered thinking and anxiety produced by THC.[7][10][11] CBD has been found to interact with a variety of different biological targets, including cannabinoid receptors and other neurotransmitter receptors.[7][12] The mechanism of action of CBD in terms of its psychoactive and therapeutic effects is not fully clear.[7]

I have/had ovarian/primary peritoneal cancer. I used thc/cbd oil pills I self made from the start. I am supposedly their “poster child”. I went thru with chemo and surgery. Oh that horror! But when I tried to tell two seperate doctors, the surgeon was all about it, and my oncologist threw a fit and said it was an anecdote. There are more than 100 studies at the NIH govt website.
It is a strict violation of the Food and Drug Administration DSHEA guidelines to make medical claims about the efficacy of CBD products in the treatment of any medical condition or symptom. Although preliminary research has shown tremendous promise of CBD oil helping people in pretty remarkable ways, legitimate CBD companies will refrain from making any direct medical claims. Be very wary of companies that defy this guideline, because if they disregard this particular rule, what other rules are they willing to ignore?
This has left some users concerned not just with which form of extracted CBD is most effective or what the proper dosage for them may be, but also with which method of supplementation gives the user the most relief in the right amount of time. Some of the most common methods include applying it sublingually, topically, or taking it in capsules. Vaping cbd is regarded by many to be the most bio-available way to administer, and as such, this has led to an increase in the demand for CBD isolate. This form of CBD is different from full-spectrum CBD extract in that it only contains CBD and none of the other cannabinoids, terpenes, or healthy fatty acids that commonly result from the whole-plant extraction process.
Because it’s already been decarboxylated, there is no need to vape CBD isolate to recieve its benefits. You can simply ingest the isolate and let it go to work. Also keep in mind that consuming isolate (as opposed to smoking a high CBD strain of cannabis) yields you higher concentrations of CBD in smaller amounts, making it a great medicine for those who need it.
In the United States, over three million people suffer from epilepsy – 470,000 of those people are children. Epilepsy is a disorder of the brain that causes seizures – of which there are over thirty different kinds, ranging from mild and infrequent to life-threatening. Not surprisingly, people with epilepsy face significant challenges – from the cost of healthcare to work limitations and social isolation.

100% organic quality is all we deal. Only select, organic growers and extraction processes are used in any product found here. Our pure CBD oil products and tinctures get to work quickly through direct, oral administration. As a capsular, daily supplement, we also have some of the best in quality CBD supplements for the easy, daily maintenance option. For those that prefer vaping, we are also proud to feature an entire line of 100% organic CBD oil vaping products including dab oils, vape oils, and even high quality vape kits.
Watch Out For: Companies that do not have test results or refuse to give them to customers. Also be wary of companies who only test one batch of finished product and then assume that all future batches will be the same – big mistake. Hemp is a product of nature and thus, no two batches will ever be identical – even in the most regulated environment. The company must provide you test results for the actual product you intend to purchase as well as the plant material used to make it – otherwise you are jeopardizing your safety and the medical efficacy of the product.
BioCBD+™ supports the findings of the US Government in patent # US 6630507 “Cannabinoids as antioxidants and neuroprotectants,” which praises Cannabidiol (CBD) for its antioxidant properties. Antioxidants are vital to not only health maintenance, but also the prevention and maintenance of oxidation associated diseases. BioCBD+™ also supports the further research into not only these areas but also into the additional therapeutic values of Cannabidiol. Evolved Ayurvedic Discoveries LTD., 11 River Street, Newry, Co. Down. Northern Ireland, BT34 2DQ; and 315 South Coast Highway, U75, Encinitas, CA 92024.
Canabidol™ CBD cannabis oil (CBD Oli) is derived from EU approved, UK & US legal, industrial hemp (Cannabis Sativa L.) The active ingredient is Cannabidiol as our products are THC free, meaning that they are non psychoactive so will not get you high. CBD Oil (Cannabidiol) is not scheduled and is found in all hemp products which makes it legal in both the UK and US. Manufactured in England to the highest standards Canabidol™ is now sent out from our United Kingdom distribution centre.  You can also purchase our range of CBD oil products direct from one of our many stores across the UK.
All of our industrial hemp is grown and extracted in accordance with the strict guidelines of the Kentucky Department of Agriculture. Utilizing a whole plant CO2 extraction allows us to draw the CBD from the plant material and filter out unnatural substances, maximizing pure CBD concentration. Derived from US grown hemp, our isolate is one of the purest isolates available with 0% THC, guaranteed.
I have this issue with neuropathy in my feet and it drives me crazy. Cant’ sleep etc… I tried some high dose CBD cream (myaderm) works really well for me. It didn’t cure anything but this is the only cream I could find that where the CBD actually stopped the pain. I think it’s because of how it’s delivered (transdermally). That seems to get down to business faster then the other ones I tried. I put some on before I go to bed and it allows me to sleep painlessly and I don’t need to take any additional pain killers… my not a doctor but it’s worth a try.
I have been suffering from scalp pain, itching and scalp sores for more than 3 years. I have seen 6 dermatologists and 5 diagnosed me with folliculitis. The 6th dermatologist felt I did not have folliculitis, but dysesthesia. I am interested in trying a cannabis scalp cream, but know nothing about this product, and where I might get it, and if it might work for me. I have had 7/7 pain for 3.5 years and need some relief other than narcotics.

Even if you are comfortable with higher doses of CBD hemp oils, incorporating isolates into your health and wellness routine takes a little more skill. For example, if you regularly take twenty milligrams of CBD oil, have you considered what that translates into with an isolate? Remember, isolates are 99-percent pure, so twenty milligrams of an isolate is much stronger than twenty milligrams of an oil-based product.


During CPC, raw oil is run through a centrifuge. The oil is pushed through a series of cells that contain a mixture of liquids such as water, methanol, or heptane. Each compound diffuses into one of the liquids depending on their affinity to it; the compounds separate into different cells along the way. The compact CPC unit uses over one thousand extraction cells in a high-speed spinning disk pack to separate and purify the desired compound. Each cell increases the purity of the desired compound until a high purity product is created. 

I have severe neuropathy in both feet and legs. I just got the CBD oil and I am interested in learning if anyone out there has had any success with this. I know each case and pain levels are different. Just would like to see some positive remarks from people who suffer with it. I am not looking for a cure just need an update on someone who took and it helped. I already know there is no cure. I need help with the pain. Thank you.
This is a topic I am asked about all the time, and have been for years: how does cannabis help sleep and health? I’ve heard that the number-two reason why people smoke or use cannabis is for sleep. Considering the recent passing of the recreational use of cannabis in California and other several states I think it is high time (pun intended!) to look at understanding CBD, one of the most active ingredients in medical cannabis.
The vast majority of CBD oils come in bottles measuring either 15 milliliters (mL), or 0.5 ounces; or 30 mL, or 1 ounce. However, CBD concentration is more important than bottle size. Concentration refers to the ratio of hemp oil solution (measured in mL) compared to the amount of CBD cannabinoid (measured in milligrams, or mg). A 15-mL bottle may contain 100 mg of CBD, 300 mg, 500 mg, or more. The higher the mg amount, the stronger the CBD oil will be. For this reason, the ‘mg’ measurement is also referred to as the oil’s strength; i.e., 400-mg oil might be called 400-strength oil.

A number of health benefits of CBD oil have been tested in vitro (i.e., with cells and tissues instead of living beings) as well as via animal studies, and some have even been examined in human clinical studies. However, until a health benefit has been validated by peer-reviewed, double-blind, placebo-controlled clinical studies, it's impossible to know for sure if CBD – or any supplement – actually has the purported effect.
^ Jump up to: a b Resstel LB, Tavares RF, Lisboa SF, Joca SR, Corrêa FM, Guimarães FS (January 2009). "5-HT1A receptors are involved in the cannabidiol-induced attenuation of behavioural and cardiovascular responses to acute restraint stress in rats". British Journal of Pharmacology. 156 (1): 181–8. doi:10.1111/j.1476-5381.2008.00046.x. PMC 2697769. PMID 19133999.
This is precisely why we here at Premium Jane do not advertise “CBD cream for arthritis for sale.” While it may be true that cannabidiol has displayed pain-relieving and anti-inflammatory effects in numerous scientific studies, will still maintain the notion that transparency is the most important thing we can offer to our customers. Those companies who blatantly urge you to buy CBD pain cream for arthritis are simply being deceptive, and not taking into consideration the current FDA status of cannabidiol as a medicine.
Disclaimer: This product is not for use by or sale to persons under the age of 18. This product should be used only as directed on the label. It should not be used if you are pregnant or nursing. Consult with a physician before use if you have a serious medical condition or use prescription medications. A Doctor’s advice should be sought before using this and any supplemental dietary product. All trademarks and copyrights are property of their respective owners and are not affiliated with nor do they endorse this product. These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. Individual results will vary. By using this site you agree to follow the Privacy Policy and all Terms & Conditions printed on this site. Void Where Prohibited By Law.

Like all of Dixie Botanicals® CBD products, our CBD Isolate is held to the same rigorous Triple Lab TestedTM standard. Accredited, independent labs carefully check the hemp oil three separate times throughout the manufacturing process to make sure its safety and potency standards are up to par. This guarantees you’re getting the CBD you expect and won’t be exposed to any mold, mildew, fungus, toxins, heavy metals, and residual solvents.
Many people want to use CBD oil for anxiety and depression, and it’s easy to understand why. After all, one of the core benefits of CBD is its ability to produce an effect that brings calm to both a restless and worried mind and a tired, weary body, without any harmful psychoactive side effects. The products are also very simple to use and boast a number of natural, organic ingredients.
CBD may help reduces REM behavior disorder in people with Parkinson’s disease. REM behavior disorder is a condition that causes people to act out physically during dreaming and REM sleep. Typically, during REM, the body is largely paralyzed, a state known as REM atonia. This immobilization keeps sleepers from reacting physically to their dreams. In REM behavior disorder, this paralysis doesn’t occur, leaving people free to move—which can lead to disruptive sleep and to injuring themselves or their sleeping partners. Cannabis may also work to reduce pain and improve sleep quality in people with Parkinson’s disease.

They may be safe, but there's one massive problem: There's practically no scientific data to support the idea that a CBD-infused topical cream is any more effective than other topical pain relievers, like Tiger Balm, BenGay, or Icy Hot. Michelle Sexton, a San Diego-based naturopathic doctor and medical research director of the Center for the Study of Cannabis and Social Policy says that her patients do seem to have a great interest in CBD ointments, and roughly 40 percent of them have indeed tried one. However, these people are in her office now because the topicals didn’t work for them. "As a medical professional, my opinion is there’s little evidence to back up the claims being made—it’s all marketing for now," she says.
Let's start with the most officially proven medical use of CBD. Earlier this year, the FDA approved the first-ever drug containing CBD, Epidiolex, to treat two rare forms of pediatric epilepsy. To get to that point, the drug's manufacturers had to do a whole lot of randomized, placebo-controlled trials on humans. They had to study how much children could take, what would happen in case of overdose, and any possible side effects that would occur.
We gave the highest points to companies that use a CBD distillate for their tinctures. The process of distillation creates an extract that is pure on a molecular level. There are people who think distillate is too pure, and that a full spectrum decarb produces a more effective tincture. But in light of the inconclusive evidence, we prefer a distillate. The process allows for a high degree of control as to the finished product. It’s also odorless and tasteless, so those tinctures tend to taste better.

Stephanie, generally, I have patients take 20 to 150mg a day for sleep +/- anxiety. Start low and go slow. Know the dosages of your product. Usually 2/3 to 3/4 of the daily dose is 1-2 hours before bedtime, and the other portion is upon waking (to improve wakefulness during the day). Other factors such as stress, hormone replacement, other meds & medical conditions, etc. play a role along with individual differences. I own a compounding pharmacy, so we see a lot of unique needs. I can't give more specific advice in this forum, but there is help!
Two dermatologists I consulted with, New York-based Whitney Bowe, MD and New Jersey-based Jeanette Jacknin, MD, both agreed that CBD’s anti-aging and anti-inflammatory benefits are clinically proven. “Studies have shown that the cannabinoids like CBD in marijuana are anti-inflammatory and anti-aging and topical CBD has proven helpful for acne, eczema, and psoriasis,” Jacknin told me. “Hemp seed oil is reputed to be the most unsaturated oil derived from the plant kingdom, so it is less pore clogging but a great moisturizer for dry, cracked skin.”
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