What if you could roll up your sleeves, tie on an apron and get in the kitchen/laboratory and create your own Cannabidiol mixtures and concoctions, in a Bill Nye meets Martha Stewart sort of way? It’s easy with CBD isolate recipes that you make or modify to help you create CBD isolate edibles. The convenience and versatility of CBD isolate hemp oil lets you do that and more!
Some companies will hide under a cloak of darkness that the Internet can provide, but it’s a pretty good sign if the company lists an honest-to-goodness phone number you can use to reach real people. The companies with inferior products will often be very difficult to reach. Before ordering, try to reach out to the company. If someone picks up the phone or gets back to you in a timely manner, you’ve probably found a company that not only takes accountability seriously, but cares about their customers and the quality of their products.
There are so many different CBD products out there to choose from, and it can be difficult to find the ones that are just right for you. To help you make an informed decision and enjoy CBD’s benefits to the fullest, we have put together several pages of invaluable information about CBD, its properties, its uses, and how YOU can best benefit from it.

Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. Pure Ratios shall have no liability for any damages, loss, injury or liability whatsoever suffered as a result of your reliance on the information contained in this site. We are unable to ship Hemp Based CBD products to the following states: Alabama, Mississippi, and Missouri. 
Thapa, D., Toguri, J. T., Szczesniak, A. M., & Kelly, A. E. M. (2017, April 1). The non-psychoactive phytocannabinoid, cannabidiol (CBD), and the synthetic derivatives, HU308 and CBD-DMH, reduces hyperalgesia and inflammation in a mouse model of corneal injury [Abstract]. FASEB Journal. Retrieved from https://www.fasebj.org/doi/abs/10.1096/fasebj.31.1_supplement.811.7

I worked about a decade for the Colorado State Dept of Health and Environment to modernize process such as the Drinking Water Compliance system. I automated the process of over 1 M certified samples from State Certified Water Samples each MONTH. If you expect it for your water (and many other services) why wouldn’t anyone expect it for a product with “CBD” on the label?

Cannabis, with its complex chemical structure, contains over 100 active cannabinoids aside from CBD. It also contains terpenes, which have anti-inflammatory properties, and are regarded as increasing the efficacy of cannabinoids. Although they are not rated as important as CBD when it comes medical benefits, some of these other cannabinoids have been found to have symptom alleviating qualities as well. The cannabinoids CBN and CBG for example, are found in most full-spectrum extracts and studies have shown that both contain anti-inflammatory, anti-bacterial, and pain relieving properties.
Lisa Hamilton, a jeweler and doula in Brooklyn, NY, knows about the side effects. She recently tried CBD for the shoulder pain that plagued her five years after an accident. Her doctor certified that she was in chronic pain, which under New York State law allowed her to buy from a state dispensary. One Friday, she swallowed two 10-mg capsules, the amount recommended at the dispensary, then took another two on Saturday. “By Sunday, it felt like I’d gotten hit by a truck. Every muscle and joint ached,” Hamilton says. She cut back to one pill a day the following week, but still felt hungover. She stopped after that.
CBD produced in the United States is by far superior to the lower quality extracts imported from overseas. With lenient regulations in countries throughout Europe and China, we urge you to take the time to properly educate yourself before buying CBD imported from overseas. With our proprietary strain and the industry's most innovative extraction techniques, we guarantee the highest quality CBD available.
Many people want to use CBD oil for anxiety and depression, and it’s easy to understand why. After all, one of the core benefits of CBD is its ability to produce an effect that brings calm to both a restless and worried mind and a tired, weary body, without any harmful psychoactive side effects. The products are also very simple to use and boast a number of natural, organic ingredients.
Winterization is just a fancy science term for cooling down a chemical substance in order to remove impurities. So, in the case of CBD isolate, winterization removes excess waxes, but it also removes the terpenes, trichomes, and flavonoids. There’s a big debate raging around whole-plant cannabis vs. isolates because the chemicals that are removed to produce an isolate can have beneficial effects when taken together.

In February 2015, the FDA sent warning letters to six companies selling CBD as a dietary supplement. The letters informed business owners that they could not sell CBD by promoting it as “intended for use in the cure, mitigation, treatment, or prevention of disease,” since it is not cleared for these purposes by the FDA. In 2016, the FDA sent letters to eight more companies.


You then take your first drop of CBD oil, wait 45 minutes, then ask the questions again. If you feel no different and there’s no change in the way you answer those questions, you increase the dose by small increments until you do notice a difference. You can continue this process over several days – and at some point, you’ll find that taking more doesn’t change your scores. That is your minimum effective dose.
This is a hugely beneficial effect of CBD. Free radicals are the culprits when it comes to oxidative damage and inflammation. But CBD’s antioxidant properties can help to combat the negative effects of everyday exposure to elements that increase the production of free radicals. These elements include pervasive, but hugely unsurprising, things like:

While both CBD and THC are present in the cannabis plant, no matter what form it takes, there are only trace amounts of psychoactive THC in industrial hemp, the plant used to make hemp textiles, hemp seeds, and most of the CBD oil on the marketplace. Long story short: using CBD oil won't make you high. (For answers to more commonly asked CBD questions, be sure to check out our forthcoming FAQ about CBD).


Many people take CBD oil for joint pain or even muscle soreness, but most would suggest that they are not as soothing or fast-acting as applying a topical CBD cream directly to the site of pain or soreness. Using a topical CBD cream for muscle soreness is also effective due to the simple mechanical effects of massaging. When you massage sore muscles, what you’re actually doing is stimulating the fibers in the contractile tissue to engage in capillary action; in other words, the fibers are actively exchanging expended blood and replenishing themselves with a new, freshly-oxygenated supply from arterioles.

When it comes to CBD oil, cheaper is most certainly not always better because the production of quality CBD oil just isn’t cheap. CO2 extraction utilizes complex equipment and a high level of expertise as opposed to the cheaper and easier chemical extraction processes that can leave residue from toxic solvents like butane, propane, and ethanol in the CBD oil. While the CO2 extraction will generally lead to a higher price tag, it does insure quality, purity, and potency – especially when used to extract CBD oil from hemp that has been organically grown in the United States.
However, this could change very soon. Not only did Senate Majority Leader Mitch McConnell recently tell hemp advocates in his home state of Kentucky that he would be introducing legislation to legalize industrial hemp as an agricultural commodity, but Epidiolex, a CBD-based drug intended for sufferers of LGS or Dravet syndrome – two epileptic conditions – was recently approved by the FDA.
CBD (Cannabidiol) is a naturally occurring compound found in the hemp plant (Cannabis Sativa). NuLeaf Naturals firmly believes that our organic CBD oil may improve the lives of individuals suffering from certain mental and physical ailments. The best of today’s science is on our side. A nonprofit called Project CBD has examined a wealth of peer-reviewed scientific research and concluded that cannabis oil may be therapeutic for individuals with conditions such as:
I have been suffering from scalp pain, itching and scalp sores for more than 3 years. I have seen 6 dermatologists and 5 diagnosed me with folliculitis. The 6th dermatologist felt I did not have folliculitis, but dysesthesia. I am interested in trying a cannabis scalp cream, but know nothing about this product, and where I might get it, and if it might work for me. I have had 7/7 pain for 3.5 years and need some relief other than narcotics.
Nuclear Magnetic Resonance (NMR) testing is much more precise than the standard High-Pressure Liquid Chromatography (HPLC), but because an NMR machine costs millions of dollars and is hard to come by in this industry, we only have limited access to one at a local university. The vast majority of NMR tests we’ve performed on our CBD isolate over the last several years have shown it to be over 99% pure cannabidiol, while standard industry HPLC tests have more variance and less reliability.

Finally, in general, we almost always recommend full spectrum tinctures over supplements made from isolates (extracts of CBD alone). Full-spectrum or whole plant tinctures take advantage of the ‘entourage effect’ that comes from combining all the naturally occurring chemicals found in the hemp plant. Isolates are great for cooking with CBD or consumers that are especially sensitive to the taste of hemp extract, but some research suggests they may be less effective for certain uses than full spectrum extracts. All but two of the brands below are made from full spectrum hemp, and the exceptions are clearly noted.


^ Jump up to: a b c d Campos AC, Moreira FA, Gomes FV, Del Bel EA, Guimarães FS (December 2012). "Multiple mechanisms involved in the large-spectrum therapeutic potential of cannabidiol in psychiatric disorders". Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences (Review). 367 (1607): 3364–78. doi:10.1098/rstb.2011.0389. PMC 3481531. PMID 23108553.
Like we mentioned a moment ago, it used to be the belief that “pure CBD,” or CBD isolate, packed the most potent punch in terms of cannabis therapy. And that would make sense too, right? If we know that CBD is primarily the active compound in the plant that provides the medical relief and therapy, then wouldn’t it make sense to make a 100% pure powder out of it?
Basically, cannabis is an umbrella term that includes both hemp and marijuana plants. Cannabis sativa is actually the scientific name of the cannabis plant (Cannabis = genus; sativa = species), and hemp and marijuana are just two different “varieties” of it (i.e. you could refer to both marijuana and hemp plants as “cannabis” plants, but you would not, for instance, refer to a “marijuana” plant as a “hemp” plant). Hopefully that’s not too confusing.
Winterization is just a fancy science term for cooling down a chemical substance in order to remove impurities. So, in the case of CBD isolate, winterization removes excess waxes, but it also removes the terpenes, trichomes, and flavonoids. There’s a big debate raging around whole-plant cannabis vs. isolates because the chemicals that are removed to produce an isolate can have beneficial effects when taken together.

It is your full responsibility to verify the customs, duties charges, and procedures in your country prior to placing your order. If customs fees and charges are refused at the time of delivery, your order will be returned and you will not receive a refund for shipment costs. IBC is also not responsible for goods that are seized by foreign or domestic customs agencies.

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