Nuclear Magnetic Resonance (NMR) testing is much more precise than the standard High-Pressure Liquid Chromatography (HPLC), but because an NMR machine costs millions of dollars and is hard to come by in this industry, we only have limited access to one at a local university. The vast majority of NMR tests we’ve performed on our CBD isolate over the last several years have shown it to be over 99% pure cannabidiol, while standard industry HPLC tests have more variance and less reliability.
Cannabis, with its complex chemical structure, contains over 100 active cannabinoids aside from CBD. It also contains terpenes, which have anti-inflammatory properties, and are regarded as increasing the efficacy of cannabinoids. Although they are not rated as important as CBD when it comes medical benefits, some of these other cannabinoids have been found to have symptom alleviating qualities as well. The cannabinoids CBN and CBG for example, are found in most full-spectrum extracts and studies have shown that both contain anti-inflammatory, anti-bacterial, and pain relieving properties.
If the ECS is affected, or the body is not producing enough endocannabinoids, these functions in the body may become unbalanced. And when the body is not producing or regulating endocannabinoids properly, ingesting natural cannabinoids or applying them topically can restore this balance. CBD differs from THC in the sense that THC mimics the natural cannabinoids in the body and binds with the cannabinoid receptors CB1 and CB2, which are found in abundance within the immune system, the gastrointestinal tract, and in the central and peripheral nervous systems. While THC binds to these receptors, CBD interacts with an enzyme called FAAH (fatty acid amide hydrolase).4
While both CBD and THC are present in the cannabis plant, no matter what form it takes, there are only trace amounts of psychoactive THC in industrial hemp, the plant used to make hemp textiles, hemp seeds, and most of the CBD oil on the marketplace. Long story short: using CBD oil won't make you high. (For answers to more commonly asked CBD questions, be sure to check out our forthcoming FAQ about CBD).
Dry mouth: As is the case with many other hemp- and marijuana-based products, CBD oil often leads to a condition known as dry mouth (or cottonmouth). This is likely due to cannabinoids altering receptors in the lower jaw that trigger salivation. In most cases, mild discomfort and stronger-than-average thirst are the only issues associated with dry mouth.
"It’s been shown that THC and CBD, when combating the myriad of symptoms and disease states, have a synergistic relationship," explains Steve Looi, Director of Origination at White Sheep Corp., a Toronto-based cannabis commercial operator and strategic investor with holdings in Canada and the US. "The compounds are more effective in each other’s presence than they would be if taken alone."
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Due to its non-psychoactive healing properties, Cannabidiol (CBD) has become a very popular option for patients seeking a natural alternative to treat conditions such as chronic pain, anxiety, epilepsy, and more. As patients start to understand how CBD can be used to alleviate their symptoms, they are often faced with a choice between using products made from CBD Isolate or Full Spectrum CBD. So, what exactly is the difference between the two?


Liquid CBD Oil/Tinctures/Extracts: Drops or tinctures should have a “suggested serving size” and the total milligrams of CBD listed on their packaging. From there, you can determine the amount of CBD you would like to ingest. Simply place the correct quantity of drops under your tongue using the dropper and hold the CBD oil in place for a minimum of 60 seconds. The 60 second hold allows for absorption via the blood vessels underneath your tongue – efficiently bypassing first-pass metabolism. Once 60 seconds has passed, swallow the CBD oil.
Jump up ^ Klein C, Karanges E, Spiro A, Wong A, Spencer J, Huynh T, Gunasekaran N, Karl T, Long LE, Huang XF, Liu K, Arnold JC, McGregor IS (November 2011). "Cannabidiol potentiates Δ⁹-tetrahydrocannabinol (THC) behavioural effects and alters THC pharmacokinetics during acute and chronic treatment in adolescent rats". Psychopharmacology. 218 (2): 443–457. doi:10.1007/s00213-011-2342-0. PMID 21667074.
Ingredients: 100 mg Hemp Flower Extract, Organic Coconut Oil, Organic Shea Butter, Cocoa Butter, Beeswax, Organic Menthol Crystals, Boswellia Extract Powder, White Willow Bark Extract, Organic Cayenne, Organic Calendula Flowers, Organic Ginger, Arnica Oil, Capsicum Oil, Sunflower Oil, Essential Oils: Wintergreen, Organic Eucalyptus, Peppermint, Lavender, and Ginger
Our CBD topical cream is legal nationwide and contains less than 0.3% THC. Our dedication to quality and customer satisfaction is what sets us apart from our competitors. We pay close attention to every detail and strive to provide our customers with the best CBD topical cream on the market. Try our CBD cream for sale and discover the natural healing powers of CBD!
This may seem like a repeat of an earlier question, but while that question related to concentration of CBD in the product, this is simply a question of how much you’re getting in total. Most bottles are labeled in a similar way – “1,000mg CBD Oil” or “1,000mg Hemp Extract” – which generally means the entire bottle contains a total of 1,000mg of CBD.

Online retailers: Most CBD oils are sold through online retailers. These establishments tend to have the widest product range, and many offer free doorstep delivery. Online retailers also frequently post product reviews, allowing buyers to compare different oils based on customer experiences to determine which is best for them. These reviews can also be used to evaluate the retailer based on customer service, delivery, and product quality.
CBD infused skin products made by Cannabis Beauty Defined are also quite popular. This is a line of skin care products with anti-aging properties. They include moisturizers, toners, exfoliators, and serums along the CBD oil. There are also a mixture of herbal extracts included to make sure the skin is well pampered. The result is a smoother, more youthful appearance to the treated area.
* * This product is not for use by or sale to persons under the age of 18. This product should be used only as directed on the label. It should not be used if you are pregnant or nursing. Consult with a physician before use if you have a serious medical condition or use prescription medications. A Doctor’s advice should be sought before using this and any supplemental dietary product. All trademarks and copyrights are property of their respective owners and are not affiliated with nor do they endorse this product. These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. Individual weight loss results will vary. By using this site, you agree to follow the Privacy Policy and all Terms & Conditions printed on this site. Void Where Prohibited by Law.
This is a topic I am asked about all the time, and have been for years: how does cannabis help sleep and health? I’ve heard that the number-two reason why people smoke or use cannabis is for sleep. Considering the recent passing of the recreational use of cannabis in California and other several states I think it is high time (pun intended!) to look at understanding CBD, one of the most active ingredients in medical cannabis.
The good news is that most of the official research done on CBD oil has shown that there are very few negative side effects from using it. However, CBD is not without some side effects. Most notably, in the clinical studies for epilepsy, sedation was one of the more common side effects. Decreased appetite and diarrhea were also seen in some patients. Depending on what other medicines they are taking, certain patients may need to have periodic blood tests to check on liver function.

Cannabis has been used medicinally for centuries, as a sleep aid, a pain and nausea reducer, to relieve anxiety and other mood problems. In the mid-1960s, scientists identified the first cannabinoid. Since then, scientists have gone on to identify more than 80 individual cannabinoids and continue to investigate them for their potential symptom-relieving and disease-fighting abilities.
Similarly, transparency is one of our top concerns when it comes to selecting the best CBD oil tinctures. Every product below is clearly labeled, so you can easily understand how much CBD oil / full spectrum hemp extract is in each bottle. You can also easily find the complete ingredients on the bottle, packaging or the company’s website. These brands are also open about where they source their hemp.
These statements have not been evaluated by the fda and are not intended to diagnose, treat, or cure any disease. Always check with your physician before starting a new dietary supplement program. Leaving our website disclaimer: if we have a research link to a website where we sell products or have product information, the exit disclaimer indicates that when you click ok you will leave the dixiebotanicals.com website and visit an external link. Links to any informational websites are provided solely as a service to our users. External links provide additional information that may be useful or interesting and has no affiliation to the promotion, sale and distribution of dixie botanicals products. The link does not constitute an endorsement of these organizations by dixie botanicals and none should be inferred. Please view our full terms of use agreement for more information and the terms and conditions governing your use of this site.

Cohen has found that chronic conditions including autoimmune diseases and pain syndromes can be helped with a 6-mg under-the-tongue tincture (the fastest delivery system) or a 25-mg capsule taken twice a day. Dosages for topical products like lotions are especially hard to determine—there’s no clarity on how much CBD gets into the system through the skin.


Made with hemp grown in Europe, PlusCBD Oil is tested in a state-of-the-art in-house laboratory for CBD levels; these findings are then validated by a third-party lab, which also tests to ensure that all Plus CBD Oil products are free of pesticides, fungicides, plant growth regulators, and residual solvents. A third lab uses advanced testing methods to ensure that all batches are free of heavy metals.
An important factor is the quality and purity of our CBD. We chose the Kentucky farm collective because of the quality of the hemp plants being grown under the Federal Farm Bill and in conjunction with the Kentucky Agricultural Department Hemp Pilot Program. There are very specific guidelines for planting, growing and the processing of the CBD isolate. As a result, the quality of the CBD produced from the whole plant is some of the purest available. We take great pride in providing our clients with an extremely pure, clean and high-quality product to those who desire CBD. Each and every product that leaves the facility is third-party tested to ensure consistency and quality.

Medical reviews published in 2017 and 2018 incorporating numerous clinical trials concluded that cannabidiol is an effective treatment for certain types of childhood epilepsy.[19][20] An orally administered cannabidiol solution (brand name Epidiolex) was approved by the US Food and Drug Administration in June 2018 as a treatment for two rare forms of childhood epilepsy, Lennox-Gastaut syndrome and Dravet syndrome.[13]


This may be a good place to point out that not all CBD products are created equal. The industry is still largely unregulated, and the quality and quantity of CBD in a given product will vary wildly. Third party testing definitely helps to monitor companies’ claims, but it’s still up to you as the consumer to do your homework on the best CBD products.

When CBD is referred to as full spectrum or whole plant CBD, it means that the CBD contains all other cannabinoids found in the marijuana plant including CBN (Cannabinol), CBG (Cannabigerol), and THCV (Tetrahydrocannabivarin), to name a few. And yes, along with these cannabinoids, Full Spectrum CBD also contains trace amounts of THC (Tetrahydrocannabinol), but in very low concentrations (up to .3%), resulting in very minimal psychoactive stimulation.
Another field in which CBD is creating a buzz is in the area of mood disorders like anxiety and depression. Both conditions have been treated with a variety of medications, courtesy of Big Pharma, that have had varying levels of success. Again, the long list of side effects can be off-putting to someone who just wants to get through the day without the sweaty tension of anxiety or the gray haze of depression.
There’s no definite amount that’s appropriate for everyone, but the ratio of CBD to THC will indicate how psychoactive the product is and if it’s legal in your state. The more CBD compared with THC, the less of a high, and vice versa. “Managing psychoactivity is key to successful cannabis therapy,” says Lee. “Amounts should be made clear on the label and lab-certified so people know what’s helping them and what’s not.”
The cannabis plant is filled with hundreds of different compounds, several of which have been studied for decades for their therapeutic benefits. The cannabis compounds that have captured the most scientific interest are known as cannabinoids. Cannabinoids are now used in treatment for a broad—and growing—range of conditions and symptoms, from sleep and pain, to anxiety and inflammation, to Parkinson’s disease and cancer.

Finally, in general, we almost always recommend full spectrum tinctures over supplements made from isolates (extracts of CBD alone). Full-spectrum or whole plant tinctures take advantage of the ‘entourage effect’ that comes from combining all the naturally occurring chemicals found in the hemp plant. Isolates are great for cooking with CBD or consumers that are especially sensitive to the taste of hemp extract, but some research suggests they may be less effective for certain uses than full spectrum extracts. All but two of the brands below are made from full spectrum hemp, and the exceptions are clearly noted.
As a representative with 2 companies that have CBD on the market and as a person with intractable pain and multple painful problems wirth my spine I can say that cbd does not work for everyone. It does nothing for me or for my mil who has a cancer like growth impeding her ability to swallow and has undergone radiation to shrink it. Everyone has a chemistry that’s personal to them for some it helps but for many it does not. With that in mind it’s a 50/50 chance of it helping and until you come out your pocket you’ll never know. Buyer beware.
The main steps – our premium hemp cultivars are extracted with an ethanol extraction system. It is then winterized to remove fats. Next, multiple rounds of rotary evaporation are used to remove plant material and other unnecessary components. The extract is then decarboxylated and transformed into a crystalline structure with a proprietary post-processing technique. The last steps are to get the extract tested by third-party laboratories, package it, and get it ready for shipment!
Two dermatologists I consulted with, New York-based Whitney Bowe, MD and New Jersey-based Jeanette Jacknin, MD, both agreed that CBD’s anti-aging and anti-inflammatory benefits are clinically proven. “Studies have shown that the cannabinoids like CBD in marijuana are anti-inflammatory and anti-aging and topical CBD has proven helpful for acne, eczema, and psoriasis,” Jacknin told me. “Hemp seed oil is reputed to be the most unsaturated oil derived from the plant kingdom, so it is less pore clogging but a great moisturizer for dry, cracked skin.”
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