CBD is responsible for a large bulk of the therapeutic qualities of the plant, and it has no psychotropic effects.  Marijuana users who are solely interested in the medicinal value of cannabis may find CBD isolate to be an extremely appealing form of the product.  If you’re looking for a CBD rich product, it intuitively makes sense to consume a product that is only CBD, right?
Additionally, CBD oil can benefit people with other medical conditions. CBD oil may be prescribed for patients with Lennox-Gastaut syndrome or Dravet syndrome, two rare forms of severe epilepsy; the medication Epidolex, a CBD oil oral solution, is typically prescribed in these instances. Many people with depression, anxiety, post-traumatic stress disorder, and other mental health disorders have also found that CBD oil has a calming, therapeutic effect when they experience symptoms. Most medical experts agree that marijuana is not particularly beneficial for these individuals, as the THC can increase the symptoms of these disorders, making CBD oil a good alternative option.

If the ECS is affected, or the body is not producing enough endocannabinoids, these functions in the body may become unbalanced. And when the body is not producing or regulating endocannabinoids properly, ingesting natural cannabinoids or applying them topically can restore this balance. CBD differs from THC in the sense that THC mimics the natural cannabinoids in the body and binds with the cannabinoid receptors CB1 and CB2, which are found in abundance within the immune system, the gastrointestinal tract, and in the central and peripheral nervous systems. While THC binds to these receptors, CBD interacts with an enzyme called FAAH (fatty acid amide hydrolase).4
The positive health benefits of CBD oil for pets are scientifically proven and we quickly learned that by taking advantage of the full spectrum of cannabinoids offered by the hemp plant, and not just CBD, Pet Releaf products are effectively activating your pet’s Endocannabinoid System (ECS). What happens when the ECS is turned on? It’s the only time 2-way communication (homeostasis) is happening within the body. Without full spectrum CBD, your pet’s brain is only able to guess where their body needs more support. When taking Pet Releaf CBD for pets, the body is able to tell the brain exactly where it’s needing more help and assistance. Because of this, Pet Releaf products are a potent anti-inflammatory and turbo boost to the immune system.
Research suggests that CBD may exert some of its pharmacological action through its inhibition of fatty acid amide hydrolase (FAAH), which may in turn increase the levels of endocannabinoids, such as anandamide, produced by the body.[8] It has also been speculated that some of the metabolites of CBD have pharmacological effects that contribute to the biological activity of CBD.[43]

Cannabis topicals are often made in the form of lotion, oil, salves, and balms. Any sort of topical cream or oil you can think of has already been given the cannabinoid treatment with CBD Topical Cream. Products of this kind are made with active cannabinoids that are absorbed into your system directly through your skin. Topicals can owe their popularity in recent times largely to the wide variety of products available. CBD has even made its way into lip balms, body butters, general cosmetics for the skin, and a number of hair care products.
Every BioCBD Plus™ product is more than just water soluble CBD. All of our products feature a proprietary Ayurvedic blend of water soluble cannabinoids, terpenes and different Ayurvedic herbs. We understand the desire to know the exact amounts of ingredients in each of our Ayurvedic blends, and we wish we could share that information with you without jeopardizing our trade secrets. What we can share with you is this Ayurvedic blend is Hemp Oil (CBD), Curcumin, Eucalyptus, Ginger, White Willow Bark & Burseraceae).
Hi Marilyn, I would recommend a topical lotion or salve to start for instant relief.. Maybe 250 to 300 mg tincture to see how you feel. For me, the salve took the pain in my hands away in under a minute. I didn't notice how much the tincture worked until I forgot to take on vacation. Pain that was pretty much gone but came back, I was tired, grumpy and felt horrible. It works, just need to find right product and dosage for you.
For the large majority of average users though, a high-quality full-spectrum CBD oil will be the better, more efficient option. These concentrated oils have delivered incredible results so far, and have been observed to effectively treat everything from anxiety, to diabetes, to severe chronic pain. And with the inevitable continued research that’s to come, it’s expected that the quality of full-spectrum products will only continue to get better and better. (And of course, given that hemp products are legal in all 50 states, you don’t even need a medical marijuana card to purchase it).
The link provides additional information that may be useful or interesting and has no aliation to the promotion, sale and distribution of Medical Marijuana Inc. products. The link does not constitute an endorsement of these organizations by Medical Marijuana Inc. and none should be inferred. Please view our full Terms Of Use Agreement for more information and the terms and conditions governing your use of this site.

You can order CBD isolate online or from the manufacturer directly. Right now, there are many stores that offer CBD isolate deals online. Nevertheless, you should order your isolate from a reputable dealer or manufacturer. That’s the only way you will get an organic and safe CBD product and always do your due diligence on making sure it is THC FREE or under the legal limit of .3%


Maintain a clear mind and active lifestyle with Endoca™ CBD hemp oil! - Hemp oil extracts have traditionally been used around the globe as medicine. A large body of evidence has indicated that the benefits of CBD hemp oil can relieve various ailments. Endoca maintains the biochemical equilibrium within the hemp plants to maximize the beneficial effects of its organic CBD oil.
I tried CBD oil and it was just as useful for pain as yoga. This expensive commodity is just another catch phrase replacement theology trying to be substituted for what used to be adequate pain control treatment. Today at least my Dr stands there and says sorry as he lowers the dose by another pill. Thank you for trying. Our last ditch effort on Earth will be no doubt be to smoke MJ..
Finally, in general, we almost always recommend full spectrum tinctures over supplements made from isolates (extracts of CBD alone). Full-spectrum or whole plant tinctures take advantage of the ‘entourage effect’ that comes from combining all the naturally occurring chemicals found in the hemp plant. Isolates are great for cooking with CBD or consumers that are especially sensitive to the taste of hemp extract, but some research suggests they may be less effective for certain uses than full spectrum extracts. All but two of the brands below are made from full spectrum hemp, and the exceptions are clearly noted.
To get almonds from an almond tree, you can just shake the tree. To get juice from an orange, you can simply squeeze the fruit. But getting CBD oil from hemp is a much more complicated process. The cheapest and easiest ways to extract CBD oil from hemp commonly involve harsh solvents that can leave chemical residue in the CBD oil. The best, and most reliable extraction method, uses carbon dioxide (CO2) under high pressure and extremely low temperatures to pull out as much CBD as possible without introducing contaminants. Once the CO2 is no longer under intense pressure, it simply evaporates, leaving virtually no trace of extraction on the CBD oil.
Kent, My mother has suffered from severe migraines since she was a child. Six weeks ago, she received the hemp oil tincture (I do not know what dosage). She does not take it daily. She rubs a drop or two on her temples at the start of a migraine. The drops worked more effectively for her than her medication did, and now that is all she uses. Hope this helps.

It's the Wild West out there. Without any federal regulatory body checking labels, consumers have very little way of knowing what they're buying when they purchase CBD oil. Bonn-Miller co-authored a study that found that 26 percent of CBD products on the market contained less CBD than their label claimed. So the amount you need for an effective dose could vary drastically, not just from product to product, but from bottle to bottle of the same product.
Royal Queen Seeds CBD Oil offers a convenient, discreet and quick way to dose yourself with a bit of CBD, no matter your situation or where you are. All of our CBD oil is created using organically grown hemp sourced from right here in Europe, extracted using the latest CO² techniques. It means our oil is 100% natural, offering pure and strong CBD. All you need to do as drop you dose under your tongue or in your food, and away you go!
Hi Bev, I am curious my husband has the exact same issues, and then ends up picking his poor head like crazy which aggravates the scalp sores. We figured out that he has extremely thick hair and the follicles are too densely packed together and his scalp cannot breathe. Since we figured that out he has been going in for hair cuts where they thin his hair out a lot as well as cut it so his scalp can breathe….. Overall he is doing much better as long as we stay on top of the hair trims and thinning cuts but if he doesn’t go in regularly he is back to the irritation. BTW topical MMJ is great but they can be very oily and have compound stuff in them that can further irritate the scalp possibly etc. so maybe not great for scalp… 🙂 I have traumatic injuries from a car accident and the MMJ topical creams have saved my life…..
Until 2017, products containing cannabidiol that are marketed for medical purposes were classed as medicines by the UK regulatory body, the Medicines and Healthcare products Regulatory Agency (MHRA) and could not be marketed without regulatory approval for the medical claims.[85] CBD oil with THC content not exceeding 0.2% was legalized throughout the UK in 2017.[citation needed] Cannabis oil, however, remained illegal to possess, buy and sell.[86]
In February 2015, the FDA sent warning letters to six companies selling CBD as a dietary supplement. The letters informed business owners that they could not sell CBD by promoting it as “intended for use in the cure, mitigation, treatment, or prevention of disease,” since it is not cleared for these purposes by the FDA. In 2016, the FDA sent letters to eight more companies.
I have idiopathic peripheral neuropathy ... the only thing they found that would work is lyrica. I picked up some CBD oil yesterday morning. I am prescribed to take 75 mg of lyrica 3x per day. I took one yesterday morning and have only used the CBD oil since. I bought the Koi brand, flavored, 250 MG. I used a full dropper yesterday late morning and a full dropper yesterday late afternoon. I used it once today (one full dropper) and I am amazingly pain free.

^ Jump up to: a b Resstel LB, Tavares RF, Lisboa SF, Joca SR, Corrêa FM, Guimarães FS (January 2009). "5-HT1A receptors are involved in the cannabidiol-induced attenuation of behavioural and cardiovascular responses to acute restraint stress in rats". British Journal of Pharmacology. 156 (1): 181–8. doi:10.1111/j.1476-5381.2008.00046.x. PMC 2697769. PMID 19133999.

I've been waiting for weeks to receive this topical to see if I finally found a product that works and I'm so happy to say that I did! I've been dealing with knee pain that my doctor has not been able to officially diagnose and treat and it's extremely painful. This is the first product that I've tried that actually relieves most of the pain and pressure so I can continue to workout and stand without being in so much pain. Thank you for creating such an amazing product!
It used to be that recreational cannabis users kept their habit on the DL, but now it seems that everyone is tuned into the magic of CBD, from your elderly neighbor using it for glaucoma to the woman in your book group using it for chronic pain relief to the folks at the dog park helping Rusty tone down his anxiety. But what is this magic substance, and more importantly, what can it do for you?
Given the results of this study, it would seem to confirm that full-spectrum extract is preferable over CBD isolate for most CBD users, but CBD isolate is still frequently used and believed by some to be more effective than full-plant extract. This belief is led by the idea that CBD is the only medically sought after cannabinoid in the cannabis plant, aside from THC. Many CBD isolate users are under the impression that by consuming only the CBD cannabinoid and no terpenes or any other "unnecessary" components of the plant, they are getting a more powerful or effective dose of CBD. When vaping a CBD extract, which as stated previously, is considered to be the most efficient and quick-acting method of administering CBD, isolate users may feel that they are taking the most efficient route to CBD consumption. While this method might be efficient, the lack of entourage effect means the benefits are reduced when compared to full-spectrum CBD consumption.

The theoretical logic is there, Gerdeman says. What exactly is that thinking? Well, there are a few different ways CBD could help regulate pain—by increasing your natural endocannabinoids, decreasing your inflammatory response, and desensitizing your pain receptors (although it’s still unclear whether this stands when absorbed topically compared to orally).

Correct Answer: Ingestible CBD oil should be comprised of coconut MCT oil and full spectrum hemp extract (the part that contains the actual CBD). It’s important that the carrier oil contains Medium Chain Triglycerides (MCT), like coconut oil, because it is easier for the body to digest. Remember that cannabinoids are best delivered to the body in either fat or alcohol as a carrier.
My mom is late stage dementia. We have tried coconut oil/black pepper/curcumin combo for years. Gives only tine bit of help, and is not something that reverses dementia. Maybe in someone who can score better than a 14 on the mme it could be of help. But cannabinoid is a different story. Cannabinoids produce better results in less time. Can't say yet that they will reverse anything though.

Jump up ^ Klein C, Karanges E, Spiro A, Wong A, Spencer J, Huynh T, Gunasekaran N, Karl T, Long LE, Huang XF, Liu K, Arnold JC, McGregor IS (November 2011). "Cannabidiol potentiates Δ⁹-tetrahydrocannabinol (THC) behavioural effects and alters THC pharmacokinetics during acute and chronic treatment in adolescent rats". Psychopharmacology. 218 (2): 443–457. doi:10.1007/s00213-011-2342-0. PMID 21667074.


CBD has been producing a whole lot of buzz in the health community of late – but perhaps not the kind of buzz you might expect from a cannabinoid. Since you’re reading this, you’ve probably heard of CBD and its many touted benefits. From chronic pain to mental health, CBD has the potential to alleviate an astonishing number of ailments. But like many, you might be fuzzy on the details. Consider this your primer on all things CBD.
Yes, there's a new type of topical ointment on the market, and it's infused with the cannabidiol (CBD) from marijuana. Manufacturers claim it can help alleviate acute pain and muscle soreness. CBD is similar to THC, except it's non-psychoactive, meaning some researchers view it as the golden child of medicinal use. (See also: Personal Trainers Reveal the Products They Use to Relieve Muscle Soreness)
I've been waiting for weeks to receive this topical to see if I finally found a product that works and I'm so happy to say that I did! I've been dealing with knee pain that my doctor has not been able to officially diagnose and treat and it's extremely painful. This is the first product that I've tried that actually relieves most of the pain and pressure so I can continue to workout and stand without being in so much pain. Thank you for creating such an amazing product!
Having run infusion workshops in Denver for the last 3 years, I have played with several recipes. Just Add Herbals has kits that include hypoallergenic mediums that you can infuse with kief, which they give you a way to extract from cannabis. Even lower quality cannabis can be used, the key is to pay attention to the genetic you are using. Kief makes dosing easier and these kits are a simple way to infuse not just salve, but tincture, massage oil, and cooking oil as well. The salve may be ideal for folliculitis – I’d be curious to hear how it does for you.
Cohen has found that chronic conditions including autoimmune diseases and pain syndromes can be helped with a 6-mg under-the-tongue tincture (the fastest delivery system) or a 25-mg capsule taken twice a day. Dosages for topical products like lotions are especially hard to determine—there’s no clarity on how much CBD gets into the system through the skin.

The wide range of benefits contained in full-spectrum CBD extracts means some CBD merchants have either ceased to sell, or scale down the promotion of CBD isolate, in comparison to the whole-plant extract variety. Companies and individuals who extract CBD themselves are realising that cannabis has more to offer medicinally than just CBD or THC, and that there is little to no reason to not include all that this "super-plant" has to offer in the extraction process.
Correct Answer: In the United States – all products should derived from organic hemp grown in the United States. Hemp grown in the European Union (EU) is acceptable (although less preferable than US-grown) ONLY if it is grown using organic methods and the company can prove the lack of pesticides, mold, and heavy metals through current test results (see below).
Cannabidiol has been found to act as an antagonist of GPR55, a G protein-coupled receptor and putative cannabinoid receptor that is expressed in the caudate nucleus and putamen in the brain.[35] It has also been found to act as an inverse agonist of GPR3, GPR6, and GPR12.[12] Although currently classified as orphan receptors, these receptors are most closely related phylogenetically to the cannabinoid receptors.[12] In addition to orphan receptors, CBD has been shown to act as a serotonin 5-HT1A receptor partial agonist,[36] and this action may be involved in its antidepressant,[37][38] anxiolytic,[38][39] and neuroprotective effects.[40][41] It is an allosteric modulator of the μ- and δ-opioid receptors as well.[42] The pharmacological effects of CBD have additionally been attributed to PPARγ agonism and intracellular calcium release.[8]
My dad has severe advanced stage Dementia. Will CBD oil help him at this point? He is now refusing to eat any solid food, but will accept most drinks.In addition, he has lost a great deal of weight even though they're giving him Mega Shakes containing a full meals worth of proteins, etc. He gets at least 4 of these a day..some which he refuses. Is his Dementia too far gone for CBD oils to help him?
CBD is showing real promise as a compound that can contribute to protecting the brain, thanks to its anti-oxidant and anti-inflammatory abilities. Scientists are investigating its role in neurogenesis and its ability to help the brain heal from injury, and as a treatment for neurodegenerative disease. Research suggests that CBD may help to reduce brain damage from stroke or other neurological injury. And CBD is increasingly looked to as a possible therapy for several neurodegenerative diseases, including Parkinson’s, Alzheimer’s, and multiple sclerosis.
Even if a topical contains active THC, it still won’t induce that intense “high” you’d get from smoking or ingesting cannabis. With most topicals, cannabinoids can’t breach the bloodstream; they only penetrate to the system of CB2 receptors. Transdermal patches, however, do deliver cannabinoids to the bloodstream and could have psychoactive effects with a high enough THC content.

INGREDIENTS: ALCOHOL DENAT., HAMAMELIS VIRGINIANA (WITCH HAZEL) WATER, WATER (AQUA), PROPYLENE GLYCOL, ALCOHOL, LIDOCAINE, POLYSORBATE 20, GLYCERIN, CANNABINOID EXTRACT, ARNICA MONTANA FLOWER EXTRACT, ALOE BARBADENSIS LEAF EXTRACT, EUCALYPTUS GLOBULUS LEAF OIL, MENTHA PIPERITA (PEPPERMINT) OIL, CAMPHOR, MENTHOL, TOCOPHERYL ACETATE, ALLANTOIN, SODIUM BENZOATE, POTASSIUM SORBATE.
Watch Out For: Companies that do not have test results or refuse to give them to customers. Also be wary of companies who only test one batch of finished product and then assume that all future batches will be the same – big mistake. Hemp is a product of nature and thus, no two batches will ever be identical – even in the most regulated environment. The company must provide you test results for the actual product you intend to purchase as well as the plant material used to make it – otherwise you are jeopardizing your safety and the medical efficacy of the product.
Cannabidiol, or CBD for short, is a natural phyto-cannabinoid (or plant-based chemical compound) found in cannabis plants, including hemp and marijuana. Unlike other cannabinoids — namely tetrahydrocannabinol, or THC — CBD does not produce any psychoactive effects, and will actually counteract these effects to a degree. CBD will induce feelings of sleepiness; for this reason, it can be an effective soporific for people who struggle to fall and/or remain asleep due to insomnia and other sleep disorders.

Our CBD Hemp Oils are extracted from our own proprietary strain of hemp grown specifically for pets, PR-33.  This strain is grown at the largest certified USDA organic hemp farm in the United States. Our joint-partnership with our farmers allows us to have complete control over our hemp plants, from seed to sale, from plant to pet we know exactly what’s going into the products you’re giving your pets.

One half ounce of CBD topical salve The Sisters of the Valley make all their products in a spiritual environment, with prayers for the people sown into every bottle and jar. This is a topical or 'rub-on' salve with multiple uses. The Sisters' products are made with high CBD strains of the cannabis plant, strains developed to have virtually no THC. These products are not psychoactive, they will not get a person 'high', and they will not cause a person to fail a drug test. By local and international government standards, the plant we use is considered 'hemp'. Seed Moon batch April 2018: > 50 mg of CBD per tin The CBD salve contains the following ingredients: 77.2% solid coconut oil infused with hemp 14.5% beeswax 3.8% liquid coconut oil infused with hemp 1.6% Vitamin E oil 1.5% calendula oil 1.4% lavender oil All products are tested for potency. Lab tests available upon request. Hand Made by the Sisters of the Valley in Cooperation with Earth and Sun Keep stored in a cool, dry place (not refrigerated). https://client.sclabs.com/sample/324987/

We gave the highest points to companies that use a CBD distillate for their tinctures. The process of distillation creates an extract that is pure on a molecular level. There are people who think distillate is too pure, and that a full spectrum decarb produces a more effective tincture. But in light of the inconclusive evidence, we prefer a distillate. The process allows for a high degree of control as to the finished product. It’s also odorless and tasteless, so those tinctures tend to taste better.

Weight plays a role in the effects of CBD oil, and bottle size should be selected based on how much you weigh. Let’s say you weigh less than 130 pounds and desire light CBD oil effects; this means that 11 mg or less will probably suffice per dose, giving roughly 40 doses from a 450-mg concentration. If you weigh more than 230 pounds and desire strong effects, then this same concentration will supply roughly 10 doses. 
We are staunch advocates of CBD and its many, amazing, scientifically-backed uses. We are also staunch advocates of our patrons and their access to the highest quality, 100% organic CBD products around. Getting the information you need, the exact product you want, and a no hassle transaction with no attached shipping charges – that’s what we are all about.
Cannabidiol can be taken into the body in multiple different ways, including by inhalation of cannabis smoke or vapor, as an aerosol spray into the cheek, and by mouth. It may be supplied as an oil containing only CBD as the active ingredient (no added THC or terpenes), a full-plant CBD-dominant hemp extract oil, capsules, dried cannabis, or as a prescription liquid solution.[1][3]
One half ounce of CBD topical salve The Sisters of the Valley make all their products in a spiritual environment, with prayers for the people sown into every bottle and jar. This is a topical or 'rub-on' salve with multiple uses. The Sisters' products are made with high CBD strains of the cannabis plant, strains developed to have virtually no THC. These products are not psychoactive, they will not get a person 'high', and they will not cause a person to fail a drug test. By local and international government standards, the plant we use is considered 'hemp'. Seed Moon batch April 2018: > 50 mg of CBD per tin The CBD salve contains the following ingredients: 77.2% solid coconut oil infused with hemp 14.5% beeswax 3.8% liquid coconut oil infused with hemp 1.6% Vitamin E oil 1.5% calendula oil 1.4% lavender oil All products are tested for potency. Lab tests available upon request. Hand Made by the Sisters of the Valley in Cooperation with Earth and Sun Keep stored in a cool, dry place (not refrigerated). https://client.sclabs.com/sample/324987/
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