Hi Colleen, it's almost a year later and I'm wondering how you're doing. I'm experiencing a recurrence of Stage 3 ovarian, originally diagnosed in 2011. I've decided to get some chemo, not sold on another 6 cycles though. As a new MMJ patient, I'm still going to go through with Rick Simpson Oil (THC+CBD,) and I just joined a program with my local dispensary to get CBD capsules for $2 each when I order them at least 30 at a time. I hope you're doing well!! I'm off to do more research on dosing. **NOTE: If you have ANY experience with CBD treatment of ovarian cancer, PLEASE respond. Thank you!!
Buying online is less reliable still because there’s no regulation or standardization. What you see on the label may not be what you are getting. A 2017 study in JAMA found that of the 84 CBD products researchers bought online, 43% had more CBD than indicated, while 26% had less, and some had unexpected THC. “There’s a 75% chance of getting a product where the CBD is mislabeled,” says Marcu, one of the study’s coauthors.
When it comes to CBD oil, cheaper is most certainly not always better because the production of quality CBD oil just isn’t cheap. CO2 extraction utilizes complex equipment and a high level of expertise as opposed to the cheaper and easier chemical extraction processes that can leave residue from toxic solvents like butane, propane, and ethanol in the CBD oil. While the CO2 extraction will generally lead to a higher price tag, it does insure quality, purity, and potency – especially when used to extract CBD oil from hemp that has been organically grown in the United States.
However, CBD isolate does have something to offer CBD users that full-spectrum extracts does not. The fact that full-spectrum extracts invariably contain low levels of THC means that some users prefer to play it safe and stick to pure CBD by itself, out of fear of failing a drug test or experiencing a form of "high", although both of these occurrences have been found to be fairly unlikely.
Any and all statements made in the ISODIOL blog in regard to Cannabinoid products are not expressed as medical claims. Our intention is to educate, not to suggest results nor to encourage action on the part of the reader. ISODIOL is not responsible for, and expressly disclaims all liability for, damages of any kind arise out of use, refrence to, or reliance on any information contained within the site. The information contained within the site is periodically updated, there is no gurantee to the accuracy of the information. Nothing on this site is intended to operate as legal advice, please seek your own legal advice.
I think being safe to eat is a moot point. These are topical products. I don’t think anybody is buying to eat them. It’s just a marketing tactic. In regards to the chapsticks, unless you were trying to literally eat the chapstick I think whatever negligible amount may make it past your lips and into your mouth, would certainly not be a health concern from any of these products. What concerns me more is there is zero efficacy with all of these products. Do they just decide over breakfast how much CBD needs to be added for the dosage to work? It’s ridiculous that they are marketing it as safe to eat, and people are buying into that bs and providing no clinical studies or research at all. Just my 2 cents

Kent, My mother has suffered from severe migraines since she was a child. Six weeks ago, she received the hemp oil tincture (I do not know what dosage). She does not take it daily. She rubs a drop or two on her temples at the start of a migraine. The drops worked more effectively for her than her medication did, and now that is all she uses. Hope this helps.
Full spectrum CBD does, however, bring with it the sticky issue of THC. The government regulates concentration levels of THC at 0.3 percent, an amount which results in minimal psychoactivity. But THC metabolites are stored in the fat cells of your body, building up over time. If you ever need to take a drug test, this could create an issue for you.

Side effects of CBD include sleepiness, decreased appetite, diarrhea, fatigue, malaise, weakness, sleeping problems, and others.[3] It does not have intoxicating effects like those caused by THC, and may have an opposing effect on disordered thinking and anxiety produced by THC.[7][10][11] CBD has been found to interact with a variety of different biological targets, including cannabinoid receptors and other neurotransmitter receptors.[7][12] The mechanism of action of CBD in terms of its psychoactive and therapeutic effects is not fully clear.[7]
Topicals are applied right to trouble areas so that the CBD oil can work directly where it’s needed most. Ingesting CBD products orally causes CBD and other compounds to enter the blood stream, which elicits full-body effects and takes up to 2 hours or more before those effects are experienced. With CBD topicals, the healing compound and other hemp-derived nutrients are almost immediately absorbed directly through your skin, allowing them to be target the affected area for quicker and more focused effects.  
Watch Out For: Companies that do not have test results or refuse to give them to customers. Also be wary of companies who only test one batch of finished product and then assume that all future batches will be the same – big mistake. Hemp is a product of nature and thus, no two batches will ever be identical – even in the most regulated environment. The company must provide you test results for the actual product you intend to purchase as well as the plant material used to make it – otherwise you are jeopardizing your safety and the medical efficacy of the product.
CBD interacts with the body through the endogenous cannabinoid system (ECS) or endocannabinoid system. First discovered in the late 1980’s, the endocannabinoid system regulates the body’s homeostasis, or general state of balance, impacting such functions as mood, sleep, appetite, hormone regulation, and pain and immune response. Like an acrobat on a highwire, as the environment around us impacts our normal balance, the endocannabinoid system “corrects” by mediating our body’s reaction to keep us level.
Kat’s Naturals offers five non-THC tinctures of varying concentrations: Heal and Naked (1,500mg), Balance (750mg), Metabolize (500mg), and Relax (300mg). All five tinctures are available in 5mL to 30mL containers, which can sustain users anywhere from five days to four weeks, depending on their dosage. Kat’s Naturals tinctures are derived from 99% pure fat soluble CBD isolate and pose no risk for yielding positive results on drug tests. For best results, Kat’s Naturals recommends ingesting three to five drops under the tongue and holding them in place for 60 seconds.
Due to its wide variety of medical benefits, CBD is used to treat a number of common conditions, including chronic pain, inflammation, seizures, insomnia, spasms, multiple sclerosis, and mental disorders such as anxiety and depression. As a topical agent, CBD oil can be directly applied to certain areas of the body as an effective means of relieving pain and soreness, reducing inflammation, and soothing inflammatory skin conditions such as psoriasis, dermatitis, and eczema.
Hi, I have had spondylolisthesis since age 11 which left me with extreme nerve pain...restless leg syndrome. Had 3 spinal ops and also had hip surgery 2 years ago. have asthma and hypothyroidism. I can deal with everything else but this nerve pain is insane. Used Gabapentin for 9 years and now its not in the market in Nairobi, Kenya where I live. Am on Lyrica, which is not working. I started Cbd oil in August but now found my body has become immune to the effects of pain releif I was getting. Can anyone suggest what strength oil/cbd supplement I should aim for? Currently am making flapjacks with weed, have one every night but this makes me high which I dont want. I still wake up in pain at night, please help.
Quality is a particular concern, because cannabis plants easily soak up heavy metals from pesticides and other contaminants, Marcu says. If you are buying online, look for a company that documents how it tests its products. (If the website doesn’t indicate this, call and ask.) “Buying from a reputable manufacturer is crucial, because it matters how the plant is cultivated and processed,” Dr. Maroon says. One clue that a company is cutting corners: too low a cost. Good CBD is pricey—a bottle of high-quality capsules is sold in Cohen’s office for $140. But for many, it’s worth the money. Roth spent $60 on her tiny bottle. But when her energy returned the day she started taking CBD, she decided that was a small price to pay.
I see products labeled CBD oil and other products labeled hemp oil and still others labeled hemp oil extract but haven’t been able to find anyone who can tell me the difference. I do know the difference between full-spectrum CBD oil and isolate and would prefer the synergistic effects of the whole plant. I notice no one answers any of the questions on this page. Hopefully, that will change. Thanks.

Given the results of this study, it would seem to confirm that full-spectrum extract is preferable over CBD isolate for most CBD users, but CBD isolate is still frequently used and believed by some to be more effective than full-plant extract. This belief is led by the idea that CBD is the only medically sought after cannabinoid in the cannabis plant, aside from THC. Many CBD isolate users are under the impression that by consuming only the CBD cannabinoid and no terpenes or any other "unnecessary" components of the plant, they are getting a more powerful or effective dose of CBD. When vaping a CBD extract, which as stated previously, is considered to be the most efficient and quick-acting method of administering CBD, isolate users may feel that they are taking the most efficient route to CBD consumption. While this method might be efficient, the lack of entourage effect means the benefits are reduced when compared to full-spectrum CBD consumption.

Another field in which CBD is creating a buzz is in the area of mood disorders like anxiety and depression. Both conditions have been treated with a variety of medications, courtesy of Big Pharma, that have had varying levels of success. Again, the long list of side effects can be off-putting to someone who just wants to get through the day without the sweaty tension of anxiety or the gray haze of depression.


Hi Colleen, it's almost a year later and I'm wondering how you're doing. I'm experiencing a recurrence of Stage 3 ovarian, originally diagnosed in 2011. I've decided to get some chemo, not sold on another 6 cycles though. As a new MMJ patient, I'm still going to go through with Rick Simpson Oil (THC+CBD,) and I just joined a program with my local dispensary to get CBD capsules for $2 each when I order them at least 30 at a time. I hope you're doing well!! I'm off to do more research on dosing. **NOTE: If you have ANY experience with CBD treatment of ovarian cancer, PLEASE respond. Thank you!!
While researchers are calling for more robust studies on the role of CBD on mood disorders, there is promising research that points to CBD’s role as an anxiolytic – which means it has anti-anxiety effects. Another study showed CBD to have antidepressant effects comparable to those of the prescription antidepressant Imipramine. We noted above that CBD increases levels of glutamate and serotonin – and it’s these same neurotransmitters that play a crucial role in mood regulation.
Some companies will hide under a cloak of darkness that the Internet can provide, but it’s a pretty good sign if the company lists an honest-to-goodness phone number you can use to reach real people. The companies with inferior products will often be very difficult to reach. Before ordering, try to reach out to the company. If someone picks up the phone or gets back to you in a timely manner, you’ve probably found a company that not only takes accountability seriously, but cares about their customers and the quality of their products.
^ Jump up to: a b c d Campos AC, Moreira FA, Gomes FV, Del Bel EA, Guimarães FS (December 2012). "Multiple mechanisms involved in the large-spectrum therapeutic potential of cannabidiol in psychiatric disorders". Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences (Review). 367 (1607): 3364–78. doi:10.1098/rstb.2011.0389. PMC 3481531. PMID 23108553.

Hello. I have stage 4 thyroid, secondary lymphoma..And many other health issues.I use 50mg of cbd vapor oil. 5 drops with each use. Total equals 250mg, about hits per dose, three times a day. I'm also on subsys, which is fentanyl. Idk about anyone but myself, but it's helped me with pain, with sleep, and in general my moods. So I dint have anything negative to say. I just hope that with time, proper diet, low dose chemo, and some other herbal usage, that I can shirk some of the cancer eating at my body... Thanks and good luck to you all.
BioCBD plus products are made from the finest, organically grown industrial hemp and Ayurvedic herbs. Their hemp is grown in Northern Europe using sustainable farming practices. BioCBD Plus is focused on creating all-natural benefits of CBD with other popular herbs, including eucalyptus, burseraceae, ginger, curcumin, white willow bark, and BioAvailable CBD . By using only simple and natural ingredients, BioCBD Plus ensures that you know exactly what goes into your supplement and how it can benefit you.
Every CBD product should make third-party lab results available, either online, in their packaging, or by request. At minimum, each tincture here offers lab results showing the levels of cannabinoids like CBD and THC, while others offer additional tests. The more information available to consumers the better. At the same time, we admit it isn’t always easy for newcomers to interpret these lab tests.
Kent, My mother has suffered from severe migraines since she was a child. Six weeks ago, she received the hemp oil tincture (I do not know what dosage). She does not take it daily. She rubs a drop or two on her temples at the start of a migraine. The drops worked more effectively for her than her medication did, and now that is all she uses. Hope this helps.
One thing to keep in mind when creating your own Cannabidiol-infused oils, be sure to accurately calculate the potency of your individual servings. Because it is over 99% pure, each milligram of CBD isolate represents a milligram of active CBD. Each 1 gram jar of RSHO™ CBD isolate contains 990 mg of Cannabidiol, which can be broken down into specific servings of any size. This gives you exact control over how you choose to add CBD to your system.
Based on reviews, smoking or vaporizing CBD vape oil seems to have less effects when compared to other methods of administering CBD, such as tinctures, capsules and sprays. On the flip side, others argue that smoking or vaporizing has less drawbacks than taking CBD orally, since ingesting CBD orally could result in inconsistent absorption and a delayed effect.
Despite the inability of CBD oil companies to cite health claims linked to their products, people buy CBD oil for pain and inflammation, anxiety, and sleep problems, and some also give it to their pets for the same reasons. In a survey conducted of its customers, CW Hemp, a family-owned provider of lab-tested CBD products, learned the number-one reason people buy their products is for anxiety, and according to a study conducted by Brightfield Group and HelloMD, 70 percent of consumers who use CBD do so because they suffer from anxiety.
Dry mouth: As is the case with many other hemp- and marijuana-based products, CBD oil often leads to a condition known as dry mouth (or cottonmouth). This is likely due to cannabinoids altering receptors in the lower jaw that trigger salivation. In most cases, mild discomfort and stronger-than-average thirst are the only issues associated with dry mouth.
All Green Roads products are handcrafted with only the highest quality hemp-derived CBD. Green Roads utilizes CO2 supercritical fluid extraction to ensure that no unwanted cannabinoids end up in CBD product concentrate. The raw CBD isolate used in Green Roads products is winterized prior to infusion into the final products to ensure that only CBD (and no unwanted plant compounds) is present when the bottle is sealed.
Customers looking to buy CBD creams will find the best CBD lotion at Green Roads World. CBD is an organic compound that is found in the industrial hemp plant. In order to produce the highest quality CBD muscle rub, Green Roads uses hemp that has been grown in the United States. The United States has a long history of growing hemp. In fact, it has been grown on our home continent since 1645! Our CBD cream for sale is a CBD topical cream. A topical cream is a product that is applied directly to the skin. CBD Pain Cream is a unique item that has been artfully crafted by a licensed pharmacist with twenty years of experience.

Cannabis topicals are often made in the form of lotion, oil, salves, and balms. Any sort of topical cream or oil you can think of has already been given the cannabinoid treatment with CBD Topical Cream. Products of this kind are made with active cannabinoids that are absorbed into your system directly through your skin. Topicals can owe their popularity in recent times largely to the wide variety of products available. CBD has even made its way into lip balms, body butters, general cosmetics for the skin, and a number of hair care products.
Each and every bottle is grown and processed with the same standards as the last guaranteeing quality and assuring potency. Made from CBD rich hemp flower sun grown in Oregon and MCT oil, Rosebud is proud to be a Vegan, Gluten Free, Non-GMO, Organic, and Sustainably Processed CO2 extract. Choose between our three potencies: 350mg, 700mg and 1000mg. 

Sagely Naturals tests its products three times: the raw cannabidiol is evaluated by extractors, then by another third party lab. Finally, when the company receives the final product, Sagely randomly selects bottles to test for the third and final time. These tests ensure that the product is devoid of GMOs, solvents, chemicals, heavy metals, pesticides, herbicides, and THC.
According to a growing body of research, CBD may play a role in the growth of new brain cells, a process known as neurogenesis. CBD is also widely recognized as having anti-oxidant and anti-inflammatory abilities, which make CBD a promising therapy for a wide range of conditions, from neurological disorders to autoimmune diseases to chronic pain and depression.
We gave the highest points to companies that use a CBD distillate for their tinctures. The process of distillation creates an extract that is pure on a molecular level. There are people who think distillate is too pure, and that a full spectrum decarb produces a more effective tincture. But in light of the inconclusive evidence, we prefer a distillate. The process allows for a high degree of control as to the finished product. It’s also odorless and tasteless, so those tinctures tend to taste better.
Marijuana & hemp are both cannabis sativa (and some marijuana is cannabis indica). But “industrial hemp” (the only source of CBD lawful in all 50 states, thanks to the Federal Farm Bill’s exemption of it from the Controlled Substances Act) CBD extract products are lawful in all 50 states, can be sold on the open market at any store (not just a licensed dispensary) or online to anyone over 18–regardless of the customer’s or mfr’s state’s medical or recreational weed laws.
Confusion may set in when we discover a product such as the Hemp Oil Care tincture, which is full-spectrum and THC-free. This product contradicts our previous statement that a full-spectrum product must contain low levels of THC. While uncommon, it is possible to manufacture a product that is full-spectrum and THC-free. As an example, we will explain the process of manufacturing the Hemp Oil Care tincture. 
The theoretical logic is there, Gerdeman says. What exactly is that thinking? Well, there are a few different ways CBD could help regulate pain—by increasing your natural endocannabinoids, decreasing your inflammatory response, and desensitizing your pain receptors (although it’s still unclear whether this stands when absorbed topically compared to orally).
This mint-green bath bomb, made by Los Angeles-based De La Beuh, combines the invigorating aromatherapy of peppermint oil with the pain relief benefits of CBD. I sat in the bath with this bath bomb soak for an hour—until the water ran cold—when I had both cramps and lower back aches, and while it doesn’t beat ingesting a painkiller, it did help soothe my pains so that I fell asleep as soon as I hit the pillow. De La Beuh sells bath bombs in many varieties—including a glittery Kaleidoscope version that will turn your bath into “unicorn” colors—so your preference just depends on your preferred aroma.
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