THC is the most well-known cannabinoid because of its psychotropic properties—it gets you high, and that’s because of the way that it interacts with the endocannabinoid system.  Although high THC levels are often huge draws for pot consumers, too much THC can have negative effects including paranoia, anxiety, and panic attacks.  Additionally, there is a huge market purely interested in the therapeutic aspects of cannabis, not the psychoactive ones.

CBD oil is similar to other products in that it is capable of being “watered down.” Some companies will try to eke out a higher profit margin by fooling their customers into thinking they’re getting more for less. It is important to pay attention to the concentration level of the CBD oil you’re buying in order to ensure you’re getting what you’re paying for. Although concentrations of CBD can vary quite a bit across the broad range of CBD products, a quality product will start off having somewhere between 250mg to 1,000mg per fluid ounce. This matters because if you were to purchase a 4 ounce bottle that contained 250mg of CBD, your concentration would be a mere 62.5 mg of CBD per ounce – hardly enough to reap the full benefits of CBD. It’s always important to look at the concentration level of the CBD you’re buying.

These statements have not been evaluated by the fda and are not intended to diagnose, treat, or cure any disease. Always check with your physician before starting a new dietary supplement program. Leaving our website disclaimer: if we have a research link to a website where we sell products or have product information, the exit disclaimer indicates that when you click ok you will leave the dixiebotanicals.com website and visit an external link. Links to any informational websites are provided solely as a service to our users. External links provide additional information that may be useful or interesting and has no affiliation to the promotion, sale and distribution of dixie botanicals products. The link does not constitute an endorsement of these organizations by dixie botanicals and none should be inferred. Please view our full terms of use agreement for more information and the terms and conditions governing your use of this site.
Bored with your run-of-the-mill vape liquids? Want to try the alternative everyone’s talking about? This Silver Blend CBD e-Liquid from Alternate Vape is a game-changer. Individually crafted, incredibly flavorful, and packed with CBD, you’ll never vape the same again. Choose from one of six imaginative and tantalizing flavors to elevate your vaping experience to a whole new level.
My mother has dementia/Alzheimers along with a broken knee that they will not repair do to her mental status. She is currently in a nursing home. I firmly believe her mental situation began with the over use of hydrocodone for over 30 years and was acerbated by the trauma of breaking and disconnecting her knee cap. Since weaning her off of her meds (still in progress) we have regained much of her consciousness. I want to try CBD to help in her recovery or to help slow down the disease. I cannot find a dosage recommendation plus the nursing home/doctor does not recommend it. I would need to give it to her when I am there visiting (about 3 - 4 times per week). Is there a recommended dosage for dementia/Alzheimers?
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The vast majority of CBD oils come in bottles measuring either 15 milliliters (mL), or 0.5 ounces; or 30 mL, or 1 ounce. However, CBD concentration is more important than bottle size. Concentration refers to the ratio of hemp oil solution (measured in mL) compared to the amount of CBD cannabinoid (measured in milligrams, or mg). A 15-mL bottle may contain 100 mg of CBD, 300 mg, 500 mg, or more. The higher the mg amount, the stronger the CBD oil will be. For this reason, the ‘mg’ measurement is also referred to as the oil’s strength; i.e., 400-mg oil might be called 400-strength oil.
Representations regarding the efficacy and safety of CBDPure have not been evaluated by the Food and Drug Administration. The FDA only evaluates foods and drugs, not supplements like these products. These products are not intended to diagnose, prevent, treat, or cure any disease. Click here and here to find evidence of a test, analysis, research, or study describing the benefits, performance or efficacy of CBD Oil based on the expertise of relevant professionals.
Cannabidiol can be taken into the body in multiple different ways, including by inhalation of cannabis smoke or vapor, as an aerosol spray into the cheek, and by mouth. It may be supplied as an oil containing only CBD as the active ingredient (no added THC or terpenes), a full-plant CBD-dominant hemp extract oil, capsules, dried cannabis, or as a prescription liquid solution.[1][3]

Jump up ^ Klein C, Karanges E, Spiro A, Wong A, Spencer J, Huynh T, Gunasekaran N, Karl T, Long LE, Huang XF, Liu K, Arnold JC, McGregor IS (November 2011). "Cannabidiol potentiates Δ⁹-tetrahydrocannabinol (THC) behavioural effects and alters THC pharmacokinetics during acute and chronic treatment in adolescent rats". Psychopharmacology. 218 (2): 443–457. doi:10.1007/s00213-011-2342-0. PMID 21667074.
That's not to say CBD-infused creams definitely won't reduce your acute pain or muscle soreness. That's because pretty much all of these creams on the market right now have other scientifically-proven analgesic compounds, like menthol, camphor, and capsaicin which are also found in other, non-CBD topical pain relievers. "Any cream with a heating or cooling sensation desensitizes the nerves to pain by distracting them with stimuli on top," Dr. Colberg explains. Plus you're often massaging the area as you apply, which improves circulation and reduces muscle spasms, he adds.

Marijuana & hemp are both cannabis sativa (and some marijuana is cannabis indica). But “industrial hemp” (the only source of CBD lawful in all 50 states, thanks to the Federal Farm Bill’s exemption of it from the Controlled Substances Act) CBD extract products are lawful in all 50 states, can be sold on the open market at any store (not just a licensed dispensary) or online to anyone over 18–regardless of the customer’s or mfr’s state’s medical or recreational weed laws.


I can’t assist with what you need, but I can tell you that I am a cancer survivor ( 15 years), with Chronic Fibro, arthritis and nerve damage . I was on prescribed pain meds for a long time. CBD has been a life saver. I have tried several of the above. For me, Bluebird is the best so far of them all. In terms of effectiveness , its heads and tails ( no pun intended) above the rest. They do have a program as well , yes. They are pricey . I also like Lazarus’s 25 mg Capsules as well.
What if you could roll up your sleeves, tie on an apron and get in the kitchen/laboratory and create your own Cannabidiol mixtures and concoctions, in a Bill Nye meets Martha Stewart sort of way? It’s easy with CBD isolate recipes that you make or modify to help you create CBD isolate edibles. The convenience and versatility of CBD isolate hemp oil lets you do that and more!
We gave the highest points to companies that use a CBD distillate for their tinctures. The process of distillation creates an extract that is pure on a molecular level. There are people who think distillate is too pure, and that a full spectrum decarb produces a more effective tincture. But in light of the inconclusive evidence, we prefer a distillate. The process allows for a high degree of control as to the finished product. It’s also odorless and tasteless, so those tinctures tend to taste better.
Previously, I had reviewed hemp-based beauty topicals and THC beauty products pioneering the way for cannabis in the skincare industry. This time, I tested the diverse range of CBD oil-based beauty products, which are both potent and legally available for shipping to most states. This is the new frontier in skincare—and these companies are paving the way. Go support them before Sephora hears about this.
It is a strict violation of the Food and Drug Administration DSHEA guidelines to make medical claims about the efficacy of CBD products in the treatment of any medical condition or symptom. Although preliminary research has shown tremendous promise of CBD oil helping people in pretty remarkable ways, legitimate CBD companies will refrain from making any direct medical claims. Be very wary of companies that defy this guideline, because if they disregard this particular rule, what other rules are they willing to ignore?
There’s also been a lot of talk lately about “microdosing” CBD. This refers to an incremental process of finding your minimum effective dose. You can do this with any concentration of CBD oil, but lower concentrations will take longer. In a 2017 article in Rolling Stone, Dr. Dustan Sulak outlines his protocol for microdosing. You can begin this process by asking yourself three questions:
Different topicals have different benefits to offer depending on the way they are processed and the ingredients that are used, so experiment with various transdermal products to see what works for you. Medical marijuana states are seeing more and more options for topical remedies as time goes on, and for sufferers of pain and inflammation, it’s worth exploring. You’d be surprised the difference that one special ingredient makes.
These statements have not been evaluated by the fda and are not intended to diagnose, treat, or cure any disease. Always check with your physician before starting a new dietary supplement program. Leaving our website disclaimer: if we have a research link to a website where we sell products or have product information, the exit disclaimer indicates that when you click ok you will leave the dixiebotanicals.com website and visit an external link. Links to any informational websites are provided solely as a service to our users. External links provide additional information that may be useful or interesting and has no affiliation to the promotion, sale and distribution of dixie botanicals products. The link does not constitute an endorsement of these organizations by dixie botanicals and none should be inferred. Please view our full terms of use agreement for more information and the terms and conditions governing your use of this site.
I used it on my mother's feet (she's 90). She is great for testing anything because she's in an incredible amount of pain and absolutely NOTHING works for her. Two hours after I applied it, she came into my room and said, "I can't believe that cream actually worked. I still don't have any pain in my toes and the bottom of my feet. It worked so well, I forgot about the pain after you put it on..." Needless to say, she looks forward to an application every evening.
Did you get an answer for this? I have the exact same scenario. I'm treating my TN with Tegretol, and recently tried CBD. I think I took too much and there are some weird drug interactions with Tegretol and I felt quite stoned....was alone and talking to myself in my head thinking I was Einstein. It freaked me out a bit but I think I took too much. I'm trying lower doses again as recently my TN seems to be resisting the meds, although I have had a lot of emotional stress, which seems to be a trigger. Thanks!! Anna
Lisa Hamilton, a jeweler and doula in Brooklyn, NY, knows about the side effects. She recently tried CBD for the shoulder pain that plagued her five years after an accident. Her doctor certified that she was in chronic pain, which under New York State law allowed her to buy from a state dispensary. One Friday, she swallowed two 10-mg capsules, the amount recommended at the dispensary, then took another two on Saturday. “By Sunday, it felt like I’d gotten hit by a truck. Every muscle and joint ached,” Hamilton says. She cut back to one pill a day the following week, but still felt hungover. She stopped after that.

Some individuals have been found to have mutations on the CNR1 gene, which is responsible for coding the CB1 receptor (a type of receptor in cells throughout your body that interacts with cannabinoids). Issues with the CNR1 gene can ultimately result in a poorly functioning endocannabinoid system, which is an important variable when figuring out how to use CBD oil.
Cannabidiol (CBD), a non-psychoactive segment of the marijuana plant, has created huge enthusiasm among researchers and physicians.  CBD Oil applies its remedial effect on an atomic level is as yet being sorted out. Cannabidiol is a pleiotropic sedate in that it produces numerous impacts through various atomic pathways. CBD Oil acts through different receptor-free channels and by official with various non-cannabinoid receptors and particle channels.
There are so many different CBD products out there to choose from, and it can be difficult to find the ones that are just right for you. To help you make an informed decision and enjoy CBD’s benefits to the fullest, we have put together several pages of invaluable information about CBD, its properties, its uses, and how YOU can best benefit from it.
Representations regarding the efficacy and safety of CBDPure have not been evaluated by the Food and Drug Administration. The FDA only evaluates foods and drugs, not supplements like these products. These products are not intended to diagnose, prevent, treat, or cure any disease. Click here and here to find evidence of a test, analysis, research, or study describing the benefits, performance or efficacy of CBD Oil based on the expertise of relevant professionals.
Yes, there's a new type of topical ointment on the market, and it's infused with the cannabidiol (CBD) from marijuana. Manufacturers claim it can help alleviate acute pain and muscle soreness. CBD is similar to THC, except it's non-psychoactive, meaning some researchers view it as the golden child of medicinal use. (See also: Personal Trainers Reveal the Products They Use to Relieve Muscle Soreness)
I think being safe to eat is a moot point. These are topical products. I don’t think anybody is buying to eat them. It’s just a marketing tactic. In regards to the chapsticks, unless you were trying to literally eat the chapstick I think whatever negligible amount may make it past your lips and into your mouth, would certainly not be a health concern from any of these products. What concerns me more is there is zero efficacy with all of these products. Do they just decide over breakfast how much CBD needs to be added for the dosage to work? It’s ridiculous that they are marketing it as safe to eat, and people are buying into that bs and providing no clinical studies or research at all. Just my 2 cents
CBD interacts with the body through the endogenous cannabinoid system (ECS) or endocannabinoid system. First discovered in the late 1980’s, the endocannabinoid system regulates the body’s homeostasis, or general state of balance, impacting such functions as mood, sleep, appetite, hormone regulation, and pain and immune response. Like an acrobat on a highwire, as the environment around us impacts our normal balance, the endocannabinoid system “corrects” by mediating our body’s reaction to keep us level.
Scientists have made a lot of progress in understanding how CBD produces its calming, pain-reducing, anti-inflammatory effects in the body—and there’s still more to learn. We know that CBD interacts with many different receptors, proteins, and other chemicals in the brain. These interactions create changes in the activity of neurotransmitters, hormones, and other cells throughout the brain and body. Through these interactions, CBD appears to be able to affect many of the body’s functions, from sleep-wake cycles and emotional regulation to inflammation, pain perception, and seizures.
The cannabis plant is filled with hundreds of different compounds, several of which have been studied for decades for their therapeutic benefits. The cannabis compounds that have captured the most scientific interest are known as cannabinoids. Cannabinoids are now used in treatment for a broad—and growing—range of conditions and symptoms, from sleep and pain, to anxiety and inflammation, to Parkinson’s disease and cancer.

CBD isolate will not show up on any drug test because it’s not made from the whole plant; traces of THC are within the legal limit & individual states are now passing laws to protect employees who are medical marijuana patients. It’s changing constantly & many states have patient advocacy groups that help new patients navigate the big learning curve.
I have had several neurological conditions like Bells Palsy three times, double vision, paralysis of left side of tongue. I have a lot of relief whenever I have pain by taking an inflamattory drug etoshine90 mg. Presently I have started taking Steroids for my facial palsy. The various pains I was having on the left side of neck, below the left ear, dizziness, pain around the head have subsided immidiately after the first dose of prendisolone 60 mg.I have read that CBD hemp oil can be useful for my condition of neurological and inflammation issues. My question is what concentrate (mg) of the oil should I take and for how long. Any brand that you may suggest that are available in the UK. Thank you.
Jump up ^ Fernández-Ruiz J, Sagredo O, Pazos MR, García C, Pertwee R, Mechoulam R, Martínez-Orgado J (February 2013). "Cannabidiol for neurodegenerative disorders: important new clinical applications for this phytocannabinoid?". British Journal of Clinical Pharmacology. 75 (2): 323–33. doi:10.1111/j.1365-2125.2012.04341.x. PMC 3579248. PMID 22625422.
The manufacturer will probably give you a recommended dosage, but bear in mind that this isn’t set in stone. What you need to find is your own minimum effective dose. “Minimum effective dose” is a medical term which refers to the amount of a substance you need for the results you want, and above which, the substance doesn’t increase in effectiveness.
Along with its better-known counterpart, THC (delta-9-tetrahydrocannabinol, the chemical that produces the marijuana high), CBD is one of more than 400 compounds found in the oils of cannabis plant species, which include marijuana and hemp. Unlike THC, CBD will not make you high. That said, this doesn’t mean CBD is not at all psychoactive, as many assert, says Jahan Marcu, Ph.D., director of experimental pharmacology and behavior at the International Research Center on Cannabis and Mental Health in New York City: “CBD does change cognition. It affects mood, which is why people take it for anxiety. And some find that it makes them more alert.”
By popular demand, we have also begun to carry several, high quality CBD pet products as well. For general purpose applications, we carry several, tasty tincture and oral spray options that are highly effective. Likewise, Pharma CBD capsules provide CBD purity via capsular ingestion. In addition, we have partnered with Therabis, the quality CBD maker of “Stop the Itch” and “Calm and Quiet”, the pet lovers’ ultimate go-to’s. Find these products by browsing our exclusive online inventory.
Finally, in general, we almost always recommend full spectrum tinctures over supplements made from isolates (extracts of CBD alone). Full-spectrum or whole plant tinctures take advantage of the ‘entourage effect’ that comes from combining all the naturally occurring chemicals found in the hemp plant. Isolates are great for cooking with CBD or consumers that are especially sensitive to the taste of hemp extract, but some research suggests they may be less effective for certain uses than full spectrum extracts. All but two of the brands below are made from full spectrum hemp, and the exceptions are clearly noted.
RSHO™ CBD isolate is derived from all-natural, superior quality hemp that is grown without the use of pesticides, herbicides, or chemical fertilizers. The CBD hemp oil is safely extracted using a solvent-free CO2 extraction process. It then undergoes a proprietary purification process to filter out the plant material and remove excess waxes. What remains is a pure isolate powder containing 99% CBD. Every batch of RSHO™ CBD isolate is Triple Lab Tested™ by ISO-certified laboratories to ensure the safety and purity of each product.
You then take your first drop of CBD oil, wait 45 minutes, then ask the questions again. If you feel no different and there’s no change in the way you answer those questions, you increase the dose by small increments until you do notice a difference. You can continue this process over several days – and at some point, you’ll find that taking more doesn’t change your scores. That is your minimum effective dose.
But there’s a big difference between the two. Hemp seed oil has been pressed from hemp seed, and it’s great for a lot of things – it’s good for you, tastes great, and can be used in soap, paint – even as biodiesel fuel. However, hemp seed oil does not contain any concentration of cannabinoids at all, including CBD. So by all means, stock up at your local natural food store. Just don’t expect to reap the benefits of a true CBD oil when you cook with hemp seed oil.
CBD Isolate offers a near endless amount uses and applications in its pure, unmodified form. The pure format also helps for precise control over amount of Cannabidiol in each dosage or serving. Pure CBD isolate is a white crystal that generally comes in either slab or powder format. The cannabinoid is extracted from CBD Oil using supercritical CO2 extraction.  

A supercritical CO2 extractor passes Carbon Dioxide through CBD Oil and plant material to extract and isolate the Cannabidiol cannabinoid. The process removes all plant matter including the oils, waxes, fatty acids, chlorophyll and more. The result is pure CBD. To activate that CBD, the extraction is decarboxylated, or heated, so that the acidic form of the cannabinoid (CBDa) will convert to the non-acidic form (CBD).  
I have been suffering from scalp pain, itching and scalp sores for more than 3 years. I have seen 6 dermatologists and 5 diagnosed me with folliculitis. The 6th dermatologist felt I did not have folliculitis, but dysesthesia. I am interested in trying a cannabis scalp cream, but know nothing about this product, and where I might get it, and if it might work for me. I have had 7/7 pain for 3.5 years and need some relief other than narcotics.

Most users find that regular application provides an analgesic effect that significantly reduces localized discomfort.2 Even though CBD is most often taken for pain relief, research is showing it to be beneficial in relieving, cramps, headaches, and psoriasis. CBD’s effects can increase the natural levels of pain-relieving endocannabinoids, decrease inflammatory responses, and desensitize pain receptors.2


It was previously believed that CBD in its isolated form was more potent and concentrated than full spectrum CBD; however, in 2015, the theory was debunked by a study from the Lautenberg Center for General Tumor Immunology in Jerusalem. In the study, researchers administered full spectrum CBD and CBD isolate to two different groups of mice. When comparing the data of the two groups, the results proved that the group administered with full spectrum CBD were provided with higher levels of relief. Furthermore, the study demonstrated that full spectrum CBD continued to provide relief as the dose increased, while CBD Isolate did not provide the same effect when there was an increase in dosage.

I think being safe to eat is a moot point. These are topical products. I don’t think anybody is buying to eat them. It’s just a marketing tactic. In regards to the chapsticks, unless you were trying to literally eat the chapstick I think whatever negligible amount may make it past your lips and into your mouth, would certainly not be a health concern from any of these products. What concerns me more is there is zero efficacy with all of these products. Do they just decide over breakfast how much CBD needs to be added for the dosage to work? It’s ridiculous that they are marketing it as safe to eat, and people are buying into that bs and providing no clinical studies or research at all. Just my 2 cents
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