The theoretical logic is there, Gerdeman says. What exactly is that thinking? Well, there are a few different ways CBD could help regulate pain—by increasing your natural endocannabinoids, decreasing your inflammatory response, and desensitizing your pain receptors (although it’s still unclear whether this stands when absorbed topically compared to orally).
NuLeaf Naturals CBD oil tinctures are all full spectrum; it is 100% organic and never made with herbicides, pesticides, or chemical fertilizers. The brand offers a full spectrum pet CBD oil tincture, as well. NuLeaf Naturals offers free shipping to all 50 states; the brand’s products are also sold in more than 200 retail locations across the country.
Given the degree to which marijuana and cannabinoid derivative use has been stigmatized in the past, their Schedule I classification as illegal substances, and lack of FDA approval, valid medical research on the effects of CBD isn’t as plentiful as it should be. Much of the anecdotal evidence, however, suggests that CBD’s neuro- protective, analgesic, and anti-inflammatory effects with regard to topical applications are promising.2

That's not to say CBD-infused creams definitely won't reduce your acute pain or muscle soreness. That's because pretty much all of these creams on the market right now have other scientifically-proven analgesic compounds, like menthol, camphor, and capsaicin which are also found in other, non-CBD topical pain relievers. "Any cream with a heating or cooling sensation desensitizes the nerves to pain by distracting them with stimuli on top," Dr. Colberg explains. Plus you're often massaging the area as you apply, which improves circulation and reduces muscle spasms, he adds.
I have crohns dibeates 2 stage kidney failure I take 6000 mg of chemicals a day when I get a flair l might lose a lot of blood I've had fistula surgery once darn mean killed me 2 more just gut surgerys little bit of gut removed I tease my gut doctor he schoold just put in a zipper any way I'm looking for something natural to try for pain also where I live if you get caught automatic life so the delima begins how much would any one suggest starting out with thanks for your time also compared to most of the folks mine seems like a minor problem on this site but I would appreciate some advice I hope all you folks have good lives and remember god always loves you even though sometimes you think he may have forgotten you
In the U.S., we live in a culture where more is often perceived as being better.  And it’s easy, without even thinking about it, to apply that approach to CBD dosing. But when it comes to CBD, more is not necessarily better. In fact, for many, less CBD is more effective. One way to determine your optimal dosage is to start with a small amount of CBD for a couple weeks and then slowly increase your dosage, carefully taking note of symptoms, until you’re seeing the results you want.

Weight plays a role in the effects of CBD oil, and bottle size should be selected based on how much you weigh. Let’s say you weigh less than 130 pounds and desire light CBD oil effects; this means that 11 mg or less will probably suffice per dose, giving roughly 40 doses from a 450-mg concentration. If you weigh more than 230 pounds and desire strong effects, then this same concentration will supply roughly 10 doses. 

I’ve been hoarding Girl Scouts Thin Mints lately (they’re especially good if you freeze them)—the chocolate is fine, but the peppermint oil is what makes them addicting enough to go through a whole sleeve without getting sick of them. I’m also trying to cut down on sugar, though, and while it would be a huge stretch to say that this peppermint oil-infused clear lip balm is a direct replacement for Girl Scout cookies, it really does have a very satisfying full-mouth taste of peppermint. The CBD oil, which soothes and facilitates healing at the same time, makes this formula an ideal balm for outdoor enthusiasts and or just those who are prone to painfully chapped lips. For those of us with long-hair-don’t-care, it’s not sticky—as a matter of fact, the formula is on the stiff side and won’t cause your hair to stick to your face, a welcome departure from many balms.
Plus CBD Oil™ products come in a variety of flavors and concentrations to suit your preferences. If you are considering CBD oil for your health, as with any supplement, we encourage you to speak with your physician and dive into the research to learn more about this promising phytonutrient. We at Plus CBD Oil™ are proud of our innovative selection of products.
Ingredients: Aloe Barbadensis (Aloe Vera) Leaf Juice*, Purified Water, Carthamus Tinctorius (Safflower) Oleosomes, Butyrospermum Parkii (Shae) Butter*, Cocos Nucifera (Coconut) Oil*, Vegetable Glycerin**, Cetearyl Olivate, Sorbitan Olivate**, Mangifera Indica (Mango) Seed Butter*, Lactobacillus Ferment (from Cabbage)**, Lactobacillus, Cocos Nucifera (Coconut) Fruit Extract**, CW Hemp Oil CO2 Extract, Mentha Piperita (Peppermint) Leaf Extract, Arnica Montana Flower Extract, Curcuma Longa (Turmeric) Root Extract, Salix Alba (Willow) Bark Extract, Cimicifuga Racemosa (Black Cohash) Root Extract, Prunus Armeniaca (Apricot) Kernel Oil*, Simmondsia Chinensis (Jojoba) Seed Oil*, Glyceryl Stearate (Palm Oil Derived), Xanthan Gum, Panthenol (Vitamin B5), Tocopheryl Acetate (Vitamin E), Cyamopsis Tetragonolobus (Guar) Gum*, Sodium Benzoate, and Potassium Sorbate.
Royal Queen Seeds CBD Oil offers a convenient, discreet and quick way to dose yourself with a bit of CBD, no matter your situation or where you are. All of our CBD oil is created using organically grown hemp sourced from right here in Europe, extracted using the latest CO² techniques. It means our oil is 100% natural, offering pure and strong CBD. All you need to do as drop you dose under your tongue or in your food, and away you go!
If you read the ingredient list, often everything in the jar is straight from mother earth. As long as that's indeed the case with the cream you have your eye on, the formula is immensely safe, chemically, says Gregory Gerdeman, Ph.D., neurophysiologist who researches cannabinoid biology and pharmacology at Eckerd College in Saint Petersburg, FL.. And since they're formulated to be topical—absorbing into the top layer of skin—and not transdermal—which would pass through the skin and into your bloodstream—there's no risk of getting high, Gerdeman explains. (P.S. Here's How Marijuana Affects Athletic Performance.)
This pocket-sized salve is perfect for travel or for sports, when you need a quick fix for your sore joints and muscles. It is also infused with arnica, meadowsweet, elderflower, calendula, ginger, vitamin E, turmeric, and other nourishing skincare ingredients that provide anti-inflammatory benefits. It’s good to know ahead of time that this salve is extremely hard to apply—there’s a lot of beeswax in there, which makes it difficult to melt enough to rub into your skin. (There is also a handy Topical Roll-On version so that you don’t have to even use your fingers—the problem is, the roll-on formula is also made with beeswax. It’s been 65 degrees in New York City all week and I still can’t get the formula to melt in the roll-on. Nothing that placing the container in a bowl of hot water won’t solve, but it’s not up to general skincare standards.)
This is a whole new idea to me and I can use any help you can offer. I suffer from post stroke pain in my thigh which sounds similar to the pain diabetics feel in their feet (sort of electric shocks shooting through my skin). I’ve had this 24/7 for about 5 years now. The 600 mg Gabapentin 3 times a day is no longer helping. A friend just suggested marijuana topicals which I had never heard of! Any recommendations?
This is precisely why we here at Premium Jane do not advertise “CBD cream for arthritis for sale.” While it may be true that cannabidiol has displayed pain-relieving and anti-inflammatory effects in numerous scientific studies, will still maintain the notion that transparency is the most important thing we can offer to our customers. Those companies who blatantly urge you to buy CBD pain cream for arthritis are simply being deceptive, and not taking into consideration the current FDA status of cannabidiol as a medicine.

Plus CBD Oil™ products come in a variety of flavors and concentrations to suit your preferences. If you are considering CBD oil for your health, as with any supplement, we encourage you to speak with your physician and dive into the research to learn more about this promising phytonutrient. We at Plus CBD Oil™ are proud of our innovative selection of products.
I have been suffering from scalp pain, itching and scalp sores for more than 3 years. I have seen 6 dermatologists and 5 diagnosed me with folliculitis. The 6th dermatologist felt I did not have folliculitis, but dysesthesia. I am interested in trying a cannabis scalp cream, but know nothing about this product, and where I might get it, and if it might work for me. I have had 7/7 pain for 3.5 years and need some relief other than narcotics.
One thing to keep in mind when creating your own Cannabidiol-infused oils, be sure to accurately calculate the potency of your individual servings. Because it is over 99% pure, each milligram of CBD isolate represents a milligram of active CBD. Each 1 gram jar of RSHO™ CBD isolate contains 990 mg of Cannabidiol, which can be broken down into specific servings of any size. This gives you exact control over how you choose to add CBD to your system.
At Charlotte's Web, we stand behind our products 100%. We work hard to ensure that our quality is second to none, and thousands of our customers agree that this difference is something you will experience. We’re so convinced our products will make a difference you can actually feel, that if any product doesn’t meet your expectations, we want you to send it back within the first 30 days of delivery and we will happily give you the opportunity to exchange for another product or receive a full refund.
The cannabis plant is filled with hundreds of different compounds, several of which have been studied for decades for their therapeutic benefits. The cannabis compounds that have captured the most scientific interest are known as cannabinoids. Cannabinoids are now used in treatment for a broad—and growing—range of conditions and symptoms, from sleep and pain, to anxiety and inflammation, to Parkinson’s disease and cancer.
CBD powder, as you can imagine, is refined into extremely small grains of CBD until it reaches a powdery texture.  This is a great option if you are looking for an easy way to add CBD to cooking and baking recipes as it mixes right in with your other ingredients. CBD crystals, on the other hand, are larger, thicker, and will arrive in crystalline form. CBD crystals are used for dabbing.  Read more about CBD dabs.
Despite what its white appearance may suggest, almost all isolates on the market today are not synthetic. Some big pharmaceutical companies have synthesized the CBD compound, but the Food and Drug Administration has not approved these synthetic substances for use outside the laboratory. The CBD isolates available online today are not from a petri dish; they originate from organic hemp plants.
A quality CBD topical cream provides the advantage of being able to apply the active therapeutic hemp extract directly to the site of aggravation or discomfort. This is particularly useful for application to joint areas or superficial muscle tissue, as the cannabidiol compound will diffuse across the dermal layers directly to the site of pain and inflammation.

All of our industrial hemp is grown and extracted in accordance with the strict guidelines of the Kentucky Department of Agriculture. Utilizing a whole plant CO2 extraction allows us to draw the CBD from the plant material and filter out unnatural substances, maximizing pure CBD concentration. Derived from US grown hemp, our isolate is one of the purest isolates available with 0% THC, guaranteed.


Jump up ^ Hayakawa K, Mishima K, Nozako M, Ogata A, Hazekawa M, Liu AX, Fujioka M, Abe K, Hasebe N, Egashira N, Iwasaki K, Fujiwara M (March 2007). "Repeated treatment with cannabidiol but not Delta9-tetrahydrocannabinol has a neuroprotective effect without the development of tolerance". Neuropharmacology. 52 (4): 1079–87. doi:10.1016/j.neuropharm.2006.11.005. PMID 17320118.

According to a recent publication from 2017, research has determined that CBD has a good safety profile, especially when compared to pharmaceuticals. The researchers concluded that “the most commonly reported side effects were tiredness, diarrhea, and changes of appetite/weight. In comparison with other drugs… CBD has a better side effect profile.” (2)
Despite the inability of CBD oil companies to cite health claims linked to their products, people buy CBD oil for pain and inflammation, anxiety, and sleep problems, and some also give it to their pets for the same reasons. In a survey conducted of its customers, CW Hemp, a family-owned provider of lab-tested CBD products, learned the number-one reason people buy their products is for anxiety, and according to a study conducted by Brightfield Group and HelloMD, 70 percent of consumers who use CBD do so because they suffer from anxiety.
CBD oil extracted from hemp — no matter how it’s consumed — works with the body’s ECS system to replenish cannabinoids and regulate homeostasis. The substance is also anti-anxiolytic, meaning it reduces feelings of anxiety — a common source of sleep problems in adults. For these reasons, hemp-based CBD oil can be highly beneficial for people with insomnia whether they struggle with sleep onset (falling asleep) or sleep maintenance (staying asleep). In addition to insomnia, CBD oil may lead to improvements for the following sleep disorders:

Hi Chris, the whole “product labeling” thing from brand to brand is definitely super confusing. Because the industry is so unregulated, companies can label their products “hemp oil,” “CBD oil,” “hemp extract oil,” etc, and there’s really no way to distinguish between them or tell what’s actually in them — unless they have a lab report. Basically, if you don’t see the word “CBD” anywhere on the label or on the product description, the oil is probably made from hemp seeds (in which case it has no CBD). The only sure way to know you’re getting an oil with CBD in it is to find something with a certified lab report showing the exact amount of CBD (and even still, some companies have been known to fudge their way around this). I know this isn’t the most clear-cut answer, but again, given how unregulated the industry is, there’s really no “perfect” answer. Hope this helps a little bit 🙂
Many people say that you should scrub your body with leftover coffee grounds because the caffeine helps get rid of cellulite. (It is actually well documented in medical literature.) But if you feel weird about dipping into the coffee machine at the office, try this CBD-infused coffee scrub, made with coconut oil and shea butter for extra moisturizing benefits, instead. I like using it when I need a little bit of medication with my exfoliation (which the coffee grounds are for)—plus, the strong scent of coffee will wake you up if you use it in the morning. If you live with anyone else, just make sure to clean the shower afterwards—coffee scrubs can be messy and staining.

BioCBD+ uses a full spectrum hemp extract.  Most CBD companies are using an isolate version of CBD.  With an isolated, single molecule, one misses out on much of the synergistic heading properties vs. taking in the whole plant. We are only interested in serving whole plant formulations. This is called the “entourage effect”. BioCBD+ does indeed contain all the cannabinoids and terpenes (as nature intended) and is completely legal to order and use no matter where you are.”  ~Ben Greenfield
Any and all statements made in the ISODIOL blog in regard to Cannabinoid products are not expressed as medical claims. Our intention is to educate, not to suggest results nor to encourage action on the part of the reader. ISODIOL is not responsible for, and expressly disclaims all liability for, damages of any kind arise out of use, refrence to, or reliance on any information contained within the site. The information contained within the site is periodically updated, there is no gurantee to the accuracy of the information. Nothing on this site is intended to operate as legal advice, please seek your own legal advice.
Sagely Naturals tests its products three times: the raw cannabidiol is evaluated by extractors, then by another third party lab. Finally, when the company receives the final product, Sagely randomly selects bottles to test for the third and final time. These tests ensure that the product is devoid of GMOs, solvents, chemicals, heavy metals, pesticides, herbicides, and THC.

...with due respect, your experience Locsta is almost precisely what happened with my....chihuahua. Degenerative disc disease, excruciating pain, prednisone worked, but couldn't keep her on it..pain killers and muscle relaxants didn't help, really thought I would have to put her down. Chi bloggers suggested CBD; gave PetReleaf a shot--like you, literally within minutes I could see the difference, in days she was pain free and now is back in charge of our world. The real key here is that with my dog, there is zero, nada, chance that there was any placebo effect...
This article may contain certain forward-looking statements and information, as defined within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934, and is subject to the Safe Harbor created by those sections. This material contains statements about expected future events and/or financial results that are forward-looking in nature and subject to risks and uncertainties. Such forward-looking statements by definition involve risks, uncertainties.
Everything you need to know about marijuana (cannabis) Marijuana, or cannabis, is the most commonly used illicit drug in the world. It alters the mood and affects nearly every organ in the body. With at least 120 active compounds, marijuana may have health benefits as well as risks. We describe these, addiction, and withdrawal. Learn more about cannabis here. Read now
Everybody has different medical needs, because of this Medix CBD hemp oil tinctures are available in different dosages ranging from 100mg – 4,500mg per bottle. The reason for such a large difference in CBD concentrations between the lowest strength bottle and the highest strength bottle is because we offer a vast and wide selection of CBD hemp oil tinctures to meet the needs of people with different medical goals.
There are thousands of unique varieties of hemp. The cultivars used for CBD oil contain significantly higher concentrations of CBD than others. Using these uniquely potent plants, it is possible to extract cannabis oil that contains significant levels of cannabidiol, as well as essential vitamins, minerals, fatty acids, terpenes, flavonoids, and other non-psychoactive cannabinoids.
Thousands of people have learned about the healing benefits of CBD, resulting in unprecedented interest in this supplement. People are using CBD oil to ease their chronic pain, and relieve symptoms of conditions ranging from arthritis to depression. Unlike its close cousin, psychoactive cannabis (‘marijuana’), CBD oil won’t make you feel high — but many users report significant relief of their symptoms. Even the World Health Organization declared CBD oil safe and worthy of deeper research.
At cbdMD, we combine premium quality and innovation to offer the purest CBD available on the market. We test our broad-spectrum CBD extractions through independent, third-party laboratories to guarantee the highest of standards. cbdMD is committed to providing the best in CBD; we stand behind the quality of our products by offering an easy-to-use service, free shipping, satisfaction guarantees, and US-based customer service.
On the other hand, marijuana-derived CBD and anything else derived from a cannabis plant was still classified by the DEA as a Schedule I drug (defined as a drug with "no currently accepted medical use and a high potential for abuse") until October 2018. In 2016, the DEA stated that all extracts containing more than one cannabinoid would remain classified as Schedule I. However, the approval of Epidiolex had an influence in changing this, and prescription CBD drugs with a THC content of below 0.1% have now been reclassified as Schedule 5, the lowest rating.
Jump up ^ Fernández-Ruiz J, Sagredo O, Pazos MR, García C, Pertwee R, Mechoulam R, Martínez-Orgado J (February 2013). "Cannabidiol for neurodegenerative disorders: important new clinical applications for this phytocannabinoid?". British Journal of Clinical Pharmacology. 75 (2): 323–33. doi:10.1111/j.1365-2125.2012.04341.x. PMC 3579248. PMID 22625422.
Bev, I am so sorry you are suffering with this condition it is horrible…… 🙁 Here is some other info. and recommendations Hubby has also used aloe vera pure clear get(not a lot of other stuff in with the aloe), and has also put coconut oil on his scalp and let it sit at night for about 20 minutes and then uses a fine tooth comb to get rid of some of the really dry flaky sores that are healing and then takes a shower and washes the oil out before we go to bed. He also had a prescription for topical stuff(forget what it was maybe clindomyacin?)that didn’t help. So what works best for him is to do the aloe vera, do the coconut oil, and keep his hair trimmed and thinned out. Depending on your hair length and thickness even though you are thinning due to the prob. I would suggest keeping hair shorter and have them thin it out with thinning shears overall, taking a multivitamin, Vit. D3 at least 2,000mg, and 10,000-20,000mcg biotin. I have thinning hair from going into to menopause but the biotin is really helping keeping it from all falling out. My hair was literally falling out in buckets before I started taking the Biotin and I think Vit. D3 has helped some too. I found out I had Vit. D3 shortage. You can get gel capsules of 10,000mcg Biotin so for awhile I took 2 a day. Aloe Vera is a anti-inflammatory so that can help, also don’t use any shampoos that have things like peppermint, rosemary, teatree oil, etc. which are irritants….. Write back eventually and let me know how you are doing…… 🙂

Hi, I had ovarian cancer stage 2 and went to do chemotherapy for 16 times in 2014. It came back last year 2016 but I did not do chemotherapy or radiation therapy as suggested by the doctor. I am taking hormone therapy at the moment. I would like to use cannabis oil but which one and how much CBD and how much THC should I take for ovarian cancer? Can anyone give some idea?. Thank you very much.
Despite what its white appearance may suggest, almost all isolates on the market today are not synthetic. Some big pharmaceutical companies have synthesized the CBD compound, but the Food and Drug Administration has not approved these synthetic substances for use outside the laboratory. The CBD isolates available online today are not from a petri dish; they originate from organic hemp plants.
I worked about a decade for the Colorado State Dept of Health and Environment to modernize process such as the Drinking Water Compliance system. I automated the process of over 1 M certified samples from State Certified Water Samples each MONTH. If you expect it for your water (and many other services) why wouldn’t anyone expect it for a product with “CBD” on the label?

Tammy et al, Through trial and error you will find a correct dosage. Try 50 mg daily....25 each 2x daily....if no results up the dosage until it works for you. Remember, there has never been a death from marijuana or CBD use. You might want to try a tincture or rub with CBD and THC. You won't get the psych high from it. Helps my friend with PArkinsons tremors. She takes 50mg of tincture and uses the rub morning and night. It is a miracle for arthritis. Good luck
Note: Pregnant women and lactating mothers should not use this product. Always consult a medical doctor before modifying your diet or using any new product. As with all products from BioCBD+, this product is not intended to diagnose, treat, cure, or prevent any disease. These statements have not been evaluated by the food and drug administration (FDA).

Finally, most of the products below simply contain hemp oil extract, mixed with a neutral carrier oil like hemp seed oil or coconut oil. While hemp seed oil is packed with nutrition, CBD brands are beginning to offer supplements with added ingredients that may offer additional benefits. We’ve included the complete ingredients of every product. Be sure to avoid any known allergies and investigate the pros and cons of any additional ingredients.


I think being safe to eat is a moot point. These are topical products. I don’t think anybody is buying to eat them. It’s just a marketing tactic. In regards to the chapsticks, unless you were trying to literally eat the chapstick I think whatever negligible amount may make it past your lips and into your mouth, would certainly not be a health concern from any of these products. What concerns me more is there is zero efficacy with all of these products. Do they just decide over breakfast how much CBD needs to be added for the dosage to work? It’s ridiculous that they are marketing it as safe to eat, and people are buying into that bs and providing no clinical studies or research at all. Just my 2 cents
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