There’s no definite amount that’s appropriate for everyone, but the ratio of CBD to THC will indicate how psychoactive the product is and if it’s legal in your state. The more CBD compared with THC, the less of a high, and vice versa. “Managing psychoactivity is key to successful cannabis therapy,” says Lee. “Amounts should be made clear on the label and lab-certified so people know what’s helping them and what’s not.”
Jump up ^ Klein C, Karanges E, Spiro A, Wong A, Spencer J, Huynh T, Gunasekaran N, Karl T, Long LE, Huang XF, Liu K, Arnold JC, McGregor IS (November 2011). "Cannabidiol potentiates Δ⁹-tetrahydrocannabinol (THC) behavioural effects and alters THC pharmacokinetics during acute and chronic treatment in adolescent rats". Psychopharmacology. 218 (2): 443–457. doi:10.1007/s00213-011-2342-0. PMID 21667074.
My grandma has advanced rheumatoid arthritis and osteoarthritis - debilitating pain and inflammation. She's on the 4th failed infusion. Nothing was working to control her pain and inflammation. I purchased the 1000mg mint CBD and the topical. I put the topical on her knees, ankles, shoulders, back, hips, and then gave her 15 1000mg drops. She instantly felt relief with the topical. She said it was a cooling pain relief. The topical smells really good.

That being said, though, it’s still important to do plenty of research and find a reliable CBD manufacturer, before you go throwing money at any old product. Since the market is still unregulated by the FDA, there are loads of phony companies out there that are selling completely bogus products. We recommend only using oils from reliable companies with a proven track record.


Given the degree to which marijuana and cannabinoid derivative use has been stigmatized in the past, their Schedule I classification as illegal substances, and lack of FDA approval, valid medical research on the effects of CBD isn’t as plentiful as it should be. Much of the anecdotal evidence, however, suggests that CBD’s neuro- protective, analgesic, and anti-inflammatory effects with regard to topical applications are promising.2
Research suggests that CBD may exert some of its pharmacological action through its inhibition of fatty acid amide hydrolase (FAAH), which may in turn increase the levels of endocannabinoids, such as anandamide, produced by the body.[8] It has also been speculated that some of the metabolites of CBD have pharmacological effects that contribute to the biological activity of CBD.[43]
Cannabidiol is currently a class B1 controlled drug in New Zealand under the Misuse of Drugs Act. It is also a prescription medicine under the Medicines Act. In 2017 the rules were changed so that anyone wanting to use it could go to the Health Ministry for approval. Prior to this, the only way to obtain a prescription was to seek the personal approval of the Minister of Health.
Until 2017, products containing cannabidiol that are marketed for medical purposes were classed as medicines by the UK regulatory body, the Medicines and Healthcare products Regulatory Agency (MHRA) and could not be marketed without regulatory approval for the medical claims.[85] CBD oil with THC content not exceeding 0.2% was legalized throughout the UK in 2017.[citation needed] Cannabis oil, however, remained illegal to possess, buy and sell.[86]
In addition to acting on the brain, CBD influences many body processes. That’s due to the endocannabinoid system (ECS), which was discovered in the 1990s, after scientists started investigating why pot produces a high. Although much less well-known than the cardiovascular, reproductive, and respiratory systems, the ECS is critical. “The ECS helps us eat, sleep, relax, forget what we don’t need to remember, and protect our bodies from harm,” Marcu says. There are more ECS receptors in the brain than there are for opioids or serotonin, plus others in the intestines, liver, pancreas, ovaries, bone cells, and elsewhere.

This peach-hued sea salt soak is the perfect Sunday afternoon bath ritual—and unlike a trendy bath bomb, it won’t turn your tub water a different color. With ingredients like magnesium flakes (stronger than Epsom salts), pink Himalayan salt, arnica, and of course, CBD extract, these crystals provide proactive therapeutic relief while also relaxing your senses with lavender and clary sage essential oils. You can also use them to soak your feet after a long run, just as you would with Epsom salts.


Dosage is important, because CBD can have side effects—the most common are tiredness, diarrhea, and changes in appetite and weight—so it’s best not to take more than you need. As CBD becomes more prevalent, says J. Michael Bostwick, M.D., a psychiatrist at Mayo Clinic in Rochester, MN, “I’m reasonably certain new kinds of side effects will emerge.”

Ian Jones is a journalist based in Manchester, England. He specialises in technology and food, with a heavy focus on vaping, CBD and medicinal drugs. He began writing professionally over 15 years ago and is a regular contributor to New Scientist, Vice and the Daily Mirror. He is also the resident CBD expert at the respected vaping website Spinfuel. He began looking at CBD in detail after discovering that it cured his mother's arthritis, and has since become a leading figure in the UK when it comes to educating people about the CBD extraction process and exploring its curative properties.
I wanted to tell people here that CBD has been very effective for my anxiety, and helps with insomnia. For me, it was a cumulative effect, after a week of one dropper of oil, I can sleep very well at night. I feel like I am not polluting my body with commercial pharmaceuticals. I wish everyone here the best, and hope it works for you as well as it has for me.
Despite what its white appearance may suggest, almost all isolates on the market today are not synthetic. Some big pharmaceutical companies have synthesized the CBD compound, but the Food and Drug Administration has not approved these synthetic substances for use outside the laboratory. The CBD isolates available online today are not from a petri dish; they originate from organic hemp plants.
There are so many different CBD products out there to choose from, and it can be difficult to find the ones that are just right for you. To help you make an informed decision and enjoy CBD’s benefits to the fullest, we have put together several pages of invaluable information about CBD, its properties, its uses, and how YOU can best benefit from it.
While full spectrum CBD has ultimately proven to be more effective than CBD Isolate and can be used to effectively treat a wide variety of ailments, it does not discredit the effectiveness of CBD Isolate. There are a wide variety of situations when CBD isolate would be preferred over Full Spectrum CBD. For example, you may not necessarily need the full capabilities of Full Spectrum CBD, or if you aren’t legally allowed to use THC. It is also important to note that other cannabinoids may cause negative reactions when isolated CBD wouldn’t (if the condition you are suffering from is critical, we definitely advise you speak to a medical consultant before trying out any version of CBD).
The chemical compounds responsible for the way marijuana effects users are known as cannabinoids.  The cannabis plant contains about 85 cannabinoids, with the two most widely discussed being CBD and THC. While THC is what is responsible for cannabis’ psychoactive properties, Cannabidiol (CBD), is non-psychoactive and comes with a lot of healing properties. CBD isolate is what it sounds like: the extraction of CBD from the cannabis plant so that the subsequent product is “pure” CBD.  Companies that do this use some kind of extraction process, likely CO2.  They remove unwanted plant material from the extraction, giving you a concentrated CBD isolate, which only amplifies the healing properties of the cannabinoid.
CBD isolate is the purest form of CBD available, and our isolate comes from USDA certified organic hemp. We third-party test all of our isolate to ensure this and results can be found on our Test Results page. CBD isolate is a white powder and mixes well with all food and drink applications. With our isolate, you’re limited by only your imagination.
...with due respect, your experience Locsta is almost precisely what happened with my....chihuahua. Degenerative disc disease, excruciating pain, prednisone worked, but couldn't keep her on it..pain killers and muscle relaxants didn't help, really thought I would have to put her down. Chi bloggers suggested CBD; gave PetReleaf a shot--like you, literally within minutes I could see the difference, in days she was pain free and now is back in charge of our world. The real key here is that with my dog, there is zero, nada, chance that there was any placebo effect...

Confusion may set in when we discover a product such as the Hemp Oil Care tincture, which is full-spectrum and THC-free. This product contradicts our previous statement that a full-spectrum product must contain low levels of THC. While uncommon, it is possible to manufacture a product that is full-spectrum and THC-free. As an example, we will explain the process of manufacturing the Hemp Oil Care tincture. 
This all serves to underline the importance of testing CBD extract for the various levels of active ingredients. If your homemade CBD extract contains a high amount of THC it could be illegal in your country and require you use either a different method of extraction, or more likely, the need to find a source of hemp that has lower THC. As more scientific literature emerges supporting the entourage effect, and increased benefits of full-spectrum CBD compared to CBD isolate, we can expect the manufacture and sale of CBD goods based around isolate to greatly reduce in the coming years.
In the U.S., we live in a culture where more is often perceived as being better.  And it’s easy, without even thinking about it, to apply that approach to CBD dosing. But when it comes to CBD, more is not necessarily better. In fact, for many, less CBD is more effective. One way to determine your optimal dosage is to start with a small amount of CBD for a couple weeks and then slowly increase your dosage, carefully taking note of symptoms, until you’re seeing the results you want.
A quality CBD topical cream provides the advantage of being able to apply the active therapeutic hemp extract directly to the site of aggravation or discomfort. This is particularly useful for application to joint areas or superficial muscle tissue, as the cannabidiol compound will diffuse across the dermal layers directly to the site of pain and inflammation.

But there’s a big difference between the two. Hemp seed oil has been pressed from hemp seed, and it’s great for a lot of things – it’s good for you, tastes great, and can be used in soap, paint – even as biodiesel fuel. However, hemp seed oil does not contain any concentration of cannabinoids at all, including CBD. So by all means, stock up at your local natural food store. Just don’t expect to reap the benefits of a true CBD oil when you cook with hemp seed oil.


If your state has legalized both compounds, look for a cream with 1:1 CBD to THC as well as another cannabinoid BCP (beta-caryophyllene) if possible, which manufacturers have seen better results with, Gerdeman suggests. Try Apothecanna's Extra Strength Relieving Creme ($20; apothecanna.com) or Whoopi & Maya's Medical Cannabis Rub (yes, that's Whoopi Goldberg's line), which was designed specifically for menstrual aches and pains (whoopiandmaya.com).

Ingredients: Helianthus annuus (Sunflower) Seed Oil, Stearic Acid (Vegetable Derived), Cetyl Alcohol (Coconut Alcohol), Sodium Hydroxide (non-GMO, mineral-salt), Citrus Grandis (Grapefruit) Seed Extract, Aloe barbadensis Leaf Juice, Ascorbic Acid (Vitamin C), Glycerin (non-GMO, vegetable-derived), Potassium Sorbate (non-GMO, mineral-salt), Xanthan Gum (non-GMO, vegetable-derived), Carthamus tinctorius (Safflower) Seed Oil*, Menthol (Mentha arvensis), Olea Europaea (Olive) Fruit Oil*, Ocimum basilicum (Basil) Leaf Oil*, Citrus aurantium bergamia (Bergamot) Fruit Oil*, Whole Hemp Derived CBD Isolate, Montana (Arnica) Flower Oil, Melaleuca alternifolia (Tea Tree) Oil, Zingiber officinale (Ginger) Root Oil*, Citrus medica limonum (Lemon) Peel Oil*, Citrus aurantifolia (Lime) Peel Oil*, Citrus aurantium dulcis (Orange) Peel Oil*, Rosmarinus officinalis (Rosemary) Leaf Extract, Salvia sclarea (Clary) Oil*, Phenoxyethanol


A number of health benefits of CBD oil have been tested in vitro (i.e., with cells and tissues instead of living beings) as well as via animal studies, and some have even been examined in human clinical studies. However, until a health benefit has been validated by peer-reviewed, double-blind, placebo-controlled clinical studies, it's impossible to know for sure if CBD – or any supplement – actually has the purported effect.
Hi Marilyn, I would recommend a topical lotion or salve to start for instant relief.. Maybe 250 to 300 mg tincture to see how you feel. For me, the salve took the pain in my hands away in under a minute. I didn't notice how much the tincture worked until I forgot to take on vacation. Pain that was pretty much gone but came back, I was tired, grumpy and felt horrible. It works, just need to find right product and dosage for you.

While most people assume CBD doesn’t contain THC, there are still trace amounts found in CBD oil that is made using the entire hemp plant. This is known as full-spectrum CBD and can be sold legally as long as it contains less than 0.3% THC. While this minuscule amount typically isn’t enough for people to feel any psychoactive effects, it can still show up in a person’s system.
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